Protein Alignment Pak and Stk10

DIOPT Version :10

• Sequence 1: NP_001138013.2
• Gene: Pak / 44039
• FlyBaseID: FBgn0267698
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: NP_062079.2
• Gene: Stk10 / 29398
• RGDID: 3779
• Length: 980
• Species: Rattus norvegicus
• Alignment Length: 304
• Identity: 115/304 - (37%)
• Similarity: 168/304 - (55%)
• Gaps: 18/304 - (5%)

  Fly   540 KKKKMSDEEILEKLRTIVSVGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPK 604
            |:|....|.:...|       |||..:..:.::|.||.|.||.|....||...|.|.:....:.:
  Rat    17 KRKSREYEHVRRDL-------DPNDVWEILGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEE 74

  Fly   605 KELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETCMDEG----QIAAV 665
            .|..|.||.::....||.:|..|.:|....:||:::|:.|||::..::.|  :|.|    ||..|
  Rat    75 LEDYIVEIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLE--LDRGLTEPQIQVV 137

  Fly   666 CREVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPE 730
            ||::|:||.|||..::||||:|:.|:|:.|:|.::|.|||..|:......||.:.:|||||||||
  Rat   138 CRQMLEALNFLHGKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPE 202

  Fly   731 VV---TRKQ--YGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKLSSAF 790
            ||   |.|.  |..|.|:|||||..|||.:.|||:...||::.|..||.:..|.:....|.|:.|
  Rat   203 VVLCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSTEF 267

  Fly   791 QDFLDQCLEVEVDRRASALDLLKHPFLKLARPLASLTPLIMAAK 834
            :|||...|:...:.|.||..||:|||:.......:|..|:..||
  Rat   268 RDFLKIALDKNPETRPSAAQLLQHPFVSTVTSNKALRELVAEAK 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak	NP_001138013.2	PBD	83..139	CDD:395634
		STKc_PAK_I	558..818	CDD:270814	107/268 (40%)
Stk10	NP_062079.2	STKc_STK10	23..314	CDD:132975	113/298 (38%)
		PKK	600..738	CDD:463600
		PKK	768..908	CDD:463600