DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak and sid1

DIOPT Version :9

Sequence 1:	NP_001138013.2	Gene:	Pak / 44039	FlyBaseID:	FBgn0267698	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_593564.1	Gene:	sid1 / 2542746	PomBaseID:	SPAC9G1.09	Length:	471	Species:	Schizosaccharomyces pombe

Alignment Length:	268	Identity:	107/268 - (39%)
Similarity:	162/268 - (60%)	Gaps:	4/268 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   566 YTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPKKELIINEILVMREN-KHPNVVNYLDS 629
            ||.:.|:|.|:.|.|:.|.|:.:|..:||||::|.........|.:.:.|..| ...||:.|...
pombe     9 YTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLSNCNSSNVIQYYGC 73

  Fly   630 YLVSEELWVVMEYLPGGSLTDVVTETCMDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLG 694
            ::....||::||::.|||::.::....::|..|:.:.||||..|.:||....||||||:.||||.
pombe    74 FVDGYTLWILMEHMDGGSVSGLLKMGRLNEQVISIILREVLYGLNYLHGQNKIHRDIKAANILLS 138

  Fly   695 LD-GSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMVEGEP 758
            .. |:|||.|||..||:|...|:|.|.||||:||||||:.:..||...|:|||||.||||..|.|
pombe   139 SSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVIQQTSYGLAADIWSLGITAIEMANGIP 203

  Fly   759 PYLNENPLKALYLIATNGKPEIKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPFLKLARPL 823
            |....:|::.::.|..:..|::  .|..|..|:||:..||::..:.|.||.:||:|||:|.|..:
pombe   204 PRATMHPMRVIFEIPQSEPPKL--DDHFSPTFRDFVSCCLDLNPNMRWSAKELLQHPFIKSAGTV 266

  Fly   824 ASLTPLIM 831
            ..:.||::
pombe   267 KDIIPLLV 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak	NP_001138013.2	PBD	83..137	CDD:279166
		STKc_PAK_I	558..818	CDD:270814	103/253 (41%)
		S_TKc	566..817	CDD:214567	102/252 (40%)
sid1	NP_593564.1	STKc_MST3_like	7..279	CDD:270786	107/268 (40%)
sid1	NP_593564.1	S_TKc	9..260	CDD:214567	102/252 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910