DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak and nak1

DIOPT Version :9

Sequence 1:	NP_001138013.2	Gene:	Pak / 44039	FlyBaseID:	FBgn0267698	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_596023.1	Gene:	nak1 / 2539963	PomBaseID:	SPBC17F3.02	Length:	652	Species:	Schizosaccharomyces pombe

Alignment Length:	263	Identity:	109/263 - (41%)
Similarity:	158/263 - (60%)	Gaps:	17/263 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   566 YTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNL-SQQPKKELIINEILVMRENKH---PNVVNY 626
            |||:|.:|:|:.|.||..|.:.|...||||.:|| :.:.:...|..|:.|:.|.|.   .|::.|
pombe    10 YTKLELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQSDVENIIKY 74

  Fly   627 LDSYLVSEELWVVMEYLPGGSLTDVVTETCMDEGQIAAVC-----REVLQALEFLHANQVIHRDI 686
            ..||||...||::|:|..|||:     .|.|:.|.|:..|     ||.||||:|:|...:|||||
pombe    75 HGSYLVGTNLWIIMDYCHGGSV-----RTLMEAGPISEPCISLILRETLQALKFIHHAGIIHRDI 134

  Fly   687 KSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVV-TRKQYGPKVDLWSLGIMA 750
            |:.|||:.:.|:|||.|||..|:::..:.||.|.:||||||||||: ..::|....|:|||||.|
pombe   135 KAANILVSMSGNVKLCDFGVAAELNINRRKRITFIGTPYWMAPEVIRDGQEYNVMADIWSLGITA 199

  Fly   751 IEMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHP 815
            .|:..|.||:..|:|.:|:||||....|.:  ....|:..::|:..||:....||..:.:|||..
pombe   200 YEIATGSPPHAKEDPFRAVYLIAHTAPPRL--NGNFSALLKEFIASCLQDVPQRRLDSSELLKSK 262

  Fly   816 FLK 818
            |:|
pombe   263 FIK 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak	NP_001138013.2	PBD	83..137	CDD:279166
		STKc_PAK_I	558..818	CDD:270814	108/261 (41%)
		S_TKc	566..817	CDD:214567	107/260 (41%)
nak1	NP_596023.1	PKc_like	8..282	CDD:304357	109/263 (41%)
nak1	NP_596023.1	S_TKc	10..264	CDD:214567	107/260 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910