Protein Alignment Pak and cst-1

DIOPT Version :10

• Sequence 1: NP_001138013.2
• Gene: Pak / 44039
• FlyBaseID: FBgn0267698
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: NP_001024575.2
• Gene: cst-1 / 180708
• WormBaseID: WBGene00017472
• Length: 497
• Species: Caenorhabditis elegans
• Alignment Length: 321
• Identity: 120/321 - (37%)
• Similarity: 187/321 - (58%)
• Gaps: 16/321 - (4%)

  Fly   532 PNTRAANAKKKKMSDEEILEKLRTIVSVGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQ 596
            |:|.::....::.|.:..  ||.:......|...:..:.|:|:|:.|:|:.||...:|..:|||:
 Worm     3 PSTDSSRRNSEEGSSDGF--KLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHRESGHVLAIKK 65

  Fly   597 MNLSQQPKKELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVV--TETCMDE 659
            :.:....::  ||.||.:|::.|...||.|..||....:||:||||...||::|::  ....:.|
 Worm    66 VPVDTDLQE--IIKEISIMQQCKSKYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSE 128

  Fly   660 GQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTP 724
            .:|:||.|:.|:.|::||..:.||||||:.||||..||..||.|||...|::...:||.|::|||
 Worm   129 QEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTVIGTP 193

  Fly   725 YWMAPEVVTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKLSSA 789
            :||||||:....|..|.|:|||||.||||.||.|||.:.:|::|:::|.|...|..|:.::.||.
 Worm   194 FWMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSE 258

  Fly   790 FQDFLDQCLEVEVDRRASALDLLKHPFLKLARPLASLTPLIMAAKE----------ATKGN 840
            |.||:..||..:.:.|.:||.|.:|.|:|.|.....:..:|..|:|          |:.||
 Worm   259 FNDFIRSCLIKKPEERKTALRLCEHTFIKNAPGCDIMQLMIQDAQEKAILGQAPMAASSGN 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak	NP_001138013.2	PBD	83..139	CDD:395634
		STKc_PAK_I	558..818	CDD:270814	107/261 (41%)
cst-1	NP_001024575.2	STKc_MST1_2	31..286	CDD:132943	106/256 (41%)
		Mst1_SARAH	446..493	CDD:463314