Protein Alignment Pak and pak6

DIOPT Version :9

• Sequence 1: NP_001138013.2
• Gene: Pak / 44039
• FlyBaseID: FBgn0267698
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: XP_017952376.1
• Gene: pak6 / 100495355
• XenbaseID: XB-GENE-960331
• Length: 655
• Species: Xenopus tropicalis
• Alignment Length: 824
• Identity: 250/824 - (30%)
• Similarity: 357/824 - (43%)
• Gaps: 234/824 - (28%)

  Fly    60 RKKKTLKSKIKGSKPSHTDSKPNISYPTNFEHTVHVGFDAVTGEFTGMPEAWARLLMNSNISKQE 124
            ||||              ..:|.||.|.||:|.||..|||..|:|.|:|..|
 Frog     3 RKKK--------------KKRPEISAPLNFQHRVHTSFDAKEGKFVGLPPQW------------- 40

  Fly   125 QKKNPQAVLDVLKWFDNTTKQRPSSKYMTNAITTHSGSSLSRVSSSSPSSTPTDSELHGSNSGGN 189
                 |.|||.|:        ||......:.||.
 Frog    41 -----QNVLDTLR--------RPKPVVDPSRITQ------------------------------- 61

  Fly   190 LIGVQLGSMTLGPNANNVAVAGQILGNHYQQQQQHLLQQQQPLLHQNHNQHHMGISQSHSYNFVG 254
               |||..|......:.:.:.|.|.|                |||....     :|...|....|
 Frog    62 ---VQLKPMKTVVRGSTIGLEGYISG----------------LLHDIEK-----LSVISSNTLRG 102

  Fly   255 HTVSSSTSQHSS--ANEDDMLGP-QHPQQQPPPP-------PVASRPERTKSIYT--RPIEDLQP 307
            ..::...:|...  ..|..:.|| |.|:|.|...       ...|:..|.::::.  ||:||
 Frog   103 SPLARRRAQSLGVLGEEKPLNGPFQIPEQIPSDKYGNYINCNGESKASRRQTMWPDYRPVED--- 164

  Fly   308 AIIPMPVAPATTPATPLQNHRTPGG---------------------ISAPAASPMMHNNATTTLD 351
                              |:..|.|                     :|.|:.|.:...:..:
 Frog   165 ------------------NYCKPNGSVFKAKSLDPGDFQGTVDLMALSIPSPSSLQKAHIAS--- 208

  Fly   352 KNKNNATPTSPTTTKTTAETEGTDATSTLLSATNPSCSTTPTTDPAPAAPRGSLVETATAHATTA 416
            |:.:..||||...::.                             .|.:||    |..||...
 Frog   209 KSFDEETPTSRQLSQI-----------------------------VPVSPR----EEGTAAKN-- 238

  Fly   417 AATVATSTTTNHHSSASSFSSFPSFHDDD----GTHHALPTIHCPTPTSSSRNSTVSFPVAVPLP 477
                 |.:||.|.....:|  .||.....    .....:.:.....|:||:|.   .|..|..||
 Frog   239 -----TDSTTKHKLLRGAF--VPSSRGQSVELLAPAQQIKSEALQGPSSSARG---VFAKAASLP 293

  Fly   478 PIVTPASPTPASIESPDLYTPEPTVAQVSAGGPSSQVAGNQIAVPQAAVAPAATP---------- 532
            |          :..|||.       .:|.:|.||..::..:...|..|.:|.:.|
 Frog   294 P----------NHLSPDF-------TRVISGAPSDSISPLRPCRPSPAGSPRSRPIQTSSTNLHL 341

  Fly   533 ------NTRAANAKKKKMSDEEILEKLRTIVSVGDPNRKYTKMEKIGQGASGTVYTAIESSTGME 591
                  .|:..|.:...::.|:....||.:|..|||.:......|||:|::|.|..|.|..:|.:
 Frog   342 CTDTFGKTQLGNQESPVVTHEQFKTALRMVVDQGDPRQLLEDYVKIGEGSTGVVCIAREKHSGRQ 406

  Fly   592 VAIKQMNLSQQPKKELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETC 656
            ||:|.|:|.:|.::||:.||:::||:.:||:||....||||.|||||:|||:.||:|||:|::|.
 Frog   407 VAVKMMDLRKQQRRELLFNEVVIMRDYQHPSVVEMYKSYLVGEELWVLMEYVQGGALTDIVSQTR 471

  Fly   657 MDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMV 721
            ::|.|||.||:.||||||:||:..|||||||||:|||.|||.:||:|||||||||.:..||.::|
 Frog   472 LNEEQIATVCKSVLQALEYLHSQGVIHRDIKSDSILLTLDGRIKLSDFGFCAQISKDVPKRKSLV 536

  Fly   722 GTPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKL 786
            ||||||||||:.|..||.:||:||||||.||||:|||||.:::|::|:..:..:..|::|...|.
 Frog   537 GTPYWMAPEVILRCSYGTEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSHKA 601

  Fly   787 SSAFQDFLDQCLEVEVDRRASALDLLKHPFLKLARPLASLTPLI 830
            |...:|||::.|..:...||:|.:||.|.||..|.....|.|||
 Frog   602 SPILRDFLERMLVRDAAERATAQELLDHFFLLQAGLPECLVPLI 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak	NP_001138013.2	PBD	83..137	CDD:279166	20/53 (38%)
		STKc_PAK_I	558..818	CDD:270814	137/259 (53%)
		S_TKc	566..817	CDD:214567	133/250 (53%)
pak6	XP_017952376.1	CRIB_PAK_like	10..55	CDD:238526	24/70 (34%)
		STKc_PAK6	359..655	CDD:270821	147/287 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D757766at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010