DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment msn and ATMAP4K ALPHA1

DIOPT Version :9

Sequence 1:	NP_524679.3	Gene:	msn / 44030	FlyBaseID:	FBgn0010909	Length:	1504	Species:	Drosophila melanogaster
Sequence 2:	NP_001185209.1	Gene:	ATMAP4K ALPHA1 / 841750	AraportID:	AT1G53165	Length:	688	Species:	Arabidopsis thaliana

Alignment Length:	731	Identity:	216/731 - (29%)
Similarity:	334/731 - (45%)	Gaps:	117/731 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 DLTALKDPAGI-FELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDV--TEDEEEEIKLEINVLKK 82
            |:..|::.||. |...|::|.|::|.|||...|:..:..||||:|:  :|||.|:|:.||:||.:
plant     3 DVAGLQEAAGTRFSQFELIGRGSFGDVYKAFDTELNKDVAIKVIDLEESEDEIEDIQKEISVLSQ 67

  Fly    83 ----YSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICRE 143
                |     |..|||:::.::      :||::|||...|||.||::  .|..|.|..||.|.|:
plant    68 CRCPY-----ITEYYGSYLHQT------KLWIIMEYMAGGSVADLLQ--PGNPLDEISIACITRD 119

  Fly   144 ILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIA 208
            :|..:.|||:...||||||..|:||::|.:||:.||||||||.|||.||.||:|||:|||||||.
plant   120 LLHAVEYLHAEGKIHRDIKAANILLSENGDVKVADFGVSAQLTRTISRRKTFVGTPFWMAPEVIQ 184

  Fly   209 CDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKKWSKKFHGFI 273
            ..|.    |:.::|:||||||.:|||:.:|||.||||||.||:|||.|||:| .:.:|:....|:
plant   185 NSEG----YNEKADIWSLGITMIEMAKGEPPLADLHPMRVLFIIPRESPPQL-DEHFSRPLKEFV 244

  Fly   274 DTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRK--QEKEREDYRYSGSDND 336
            ...|.|...:||..:.||||.|||:.....::       ::|.::|.  |.||.|:...:|
plant   245 SFCLKKAPAERPNAKELLKHRFIKNARKSPKL-------LERIRERPKYQVKEDEEIPTNG---- 298

  Fly   337 DDEPQLAGEHSSIV--------QAPGGDTLRRNFQ---QIQEGRLAAEQQQQHHLMAQAQAQAAA 390
               |:...|.|..|        |...|..|.:...   |::..|.|.     ..........|..
plant   299 ---PKAPAESSGTVRVAKDERGQGTSGTRLDKWLDKCFQVKTVRNAG-----WDFSIGGSQGAGT 355

  Fly   391 AHAAAQAQAQLQQQQQQAAAAAAAAAHAAQQAQQAAQQAQAQQPQANRQPKPPSRQQVEEPGPPA 455
            ..|....||:.::|:          .::.|.:|:.::.:.:|.......|      ::.|.|...
plant   356 VRALKPPQARERRQE----------VNSNQTSQKTSRTSGSQLSSTFGVP------EISEGGFNK 404

  Fly   456 RPPQRLIVVPDPPHANRPLPPTPKCGEPAGQTPQQQQRNSQNNFKPSLPPRRPEPQPQTAAGGQG 520
            |...:        :..:....:...|....::|:..|.:|....:.|...|.......:.:|...
plant   405 RDSYQ--------NDYQEEDDSSGSGTVVIRSPRSSQSSSMFRDQSSGSTRYTSFDDASTSGTVV 461

  Fly   521 SQQQAQPEAPPRNNRQSSGLSSSGGSASGGGGSSKPAAALPQQSNNHLGQPVNPLDPLDSSDSDS 585
            .:.|......||..|...||.....|||....|:...|.|..::....|   |..:.|.:...:.
plant   462 VRGQNDDSGSPRTPRSRLGLQERSSSASEDSISNLAEAKLALEAGFRRG---NARERLGNGKVNK 523

  Fly   586 EPDEPNDRA---RNDGTLLASDPPKPLPGLGPVSEDANTTTPLSHGSGGPPNRPLPPTPD---DD 644
            ..::..|.:   ||...  .||..:|:.....||:|....:.|:..|.......||...:   .|
plant   524 RREQATDNSDYLRNSRD--HSDKQRPVMRSQQVSDDEEDDSKLASLSASLSLLLLPSLKEAVGGD 586

  Fly   645 DQAG------DRTLI-MKRK----LEQNINRL-QKSASTSQANV-----------TPSRRGDESN 686
            |..|      .|:|: |:|:    .|..|.:| ::..||.:.:|           ..:...|..|
plant   587 DSKGTIGHRVSRSLVKMEREKPGSSEAFIAKLIEQLGSTKEVSVKEVQDMAIRVFAKTMNNDAEN 651

  Fly   687 LLRDWDFDRFFPKNAN 702
            ..:  ...:.|..|||
plant   652 KRK--QASKEFSSNAN 665

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	129/277 (47%)
		S_TKc	32..296	CDD:214567	126/269 (47%)
		CNH	1183..1484	CDD:214481
ATMAP4K ALPHA1	NP_001185209.1	STKc_MST3_like	14..287	CDD:270786	131/297 (44%)
ATMAP4K ALPHA1	NP_001185209.1	S_TKc	19..267	CDD:214567	125/265 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910