DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment msn and AT4G10730

DIOPT Version :9

Sequence 1:	NP_524679.3	Gene:	msn / 44030	FlyBaseID:	FBgn0010909	Length:	1504	Species:	Drosophila melanogaster
Sequence 2:	NP_192811.4	Gene:	AT4G10730 / 826667	AraportID:	AT4G10730	Length:	711	Species:	Arabidopsis thaliana

Alignment Length:	754	Identity:	181/754 - (24%)
Similarity:	288/754 - (38%)	Gaps:	192/754 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 FELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDV--TEDEEEEIKLEINVLKKYSNHRNIATYYG 94
            ::|:|.||.|....|::..:..|.::.|||.:|:  .....::|:.|...: ...:|.|:...:.
plant    47 YKLMEEVGYGASAVVHRAIYLPTNEVVAIKSLDLDRCNSNLDDIRREAQTM-TLIDHPNVIKSFC 110

  Fly    95 AFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHR 159
            :|      ..|..||:||.:...||...|:|:......:|..|..:.:|.|:.|.|||....|||
plant   111 SF------AVDHHLWVVMPFMAQGSCLHLMKAAYPDGFEEAAICSMLKETLKALDYLHRQGHIHR 169

  Fly   160 DIKGQNVLLTDNAEVKLVDFGVSAQL----DRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNR 220
            |:|..|:||.|..|:||.||||||.|    ||. ..||||:|||.||||||:    .|.:.|:::
plant   170 DVKAGNILLDDTGEIKLGDFGVSACLFDNGDRQ-RARNTFVGTPCWMAPEVL----QPGSGYNSK 229

  Fly   221 SDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRL---KSKKWSKKFHGFIDTVLVKDYH 282
            :|:||.||||||:|....|.....||:.|.:..:|:||.|   :.||:||.|...:...||||..
plant   230 ADIWSFGITALELAHGHAPFSKYPPMKVLLMTIQNAPPGLDYDRDKKFSKSFKELVALCLVKDQT 294

  Fly   283 QRPYTENLLKHGFIKD-QPTD---------------RQVRIQLKD----------HIDRCKKRKQ 321
            :||..|.||||.|.|: :|.:               |...:|.||          ..|:....:.
plant   295 KRPTAEKLLKHSFFKNVKPPEICVKKLFVDLPPLWTRVKALQAKDAAQLALKGMASADQDAISQS 359

  Fly   322 EKER---------EDYRYSGS--DNDDDEPQLAGEHSSIVQAPGGDTLRRNFQQIQEGRLAAEQQ 375
            |.:|         ||.:...|  |:||...:...|..|.     |:.|.....  ..|:::..|.
plant   360 EYQRGVSAWNFNIEDLKEQASLLDDDDILTESREEEESF-----GEQLHNKVN--DRGQVSGSQL 417

  Fly   376 QQHHLMAQAQAQAAAAHAAAQAQAQLQQQQQQAAAAAAAAAHAAQQAQQAAQQAQA--------- 431
            ...::..:.:|      :..:....:.:::....:..::....|..::|...||:.
plant   418 LSENMNGKEKA------SDTEVVEPICEEKSTLNSTTSSVEQPASSSEQDVPQAKGKPVRLQTHS 476

  Fly   432 --------------------QQPQANRQPKPPSRQQVEEPGPPARPPQRLIVVPDPPHANRPLPP 476
                                ::.::.||.|...|:.....||        :.:|:...||....|
plant   477 GPLSSGVVLINSDSEKVHGYERSESERQLKSSVRRAPSFSGP--------LNLPNRASANSLSAP 533

  Fly   477 TPKCGEPAGQTPQQQQRNSQNNFKPSLPPRRPEPQPQTAAGGQGSQQQAQPEAPPRNNRQSSGLS 541
            .                .|...|:.|:..:......|..  |:.|...        .|...:..|
plant   534 I----------------KSSGGFRDSIDDKSKANVVQIK--GRFSVTS--------ENLDLARAS 572

  Fly   542 SSGGSASGGG---GSSKPAAALPQQSNNHLGQPVNPLDPLDSSDSDSEPDEPNDRARNDGTLLAS 603
            ....|||.|.   .|..|.....::|::||...:..|..|...:|
plant   573 PLRKSASVGNWILDSKMPTGQAIKESSSHLSFIIPQLQNLFQQNS-------------------- 617

  Fly   604 DPPKPLPGLGPVSED-----ANTTTPLSHGSGGPPNRPLPPTPDDDDQAG----------DRTLI 653
                       :.:|     .||....:..:.|..|..|||.|...|..|          :|.|:
plant   618 -----------MQQDLIMNLVNTLQQAAETTDGSQNGKLPPLPRGSDSNGTVVELTAAERERLLL 671

  Fly   654 MK--------RKLEQNINRLQKSASTSQANVTPSRRGDE 684
            .|        ::|.:.: .::||..|.......|..|.|
plant   672 TKITELRARMKELTEEL-EVEKSKQTQLQQKLKSVTGRE 709

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	103/272 (38%)
		S_TKc	32..296	CDD:214567	103/272 (38%)
		CNH	1183..1484	CDD:214481
AT4G10730	NP_192811.4	STKc_OSR1_SPAK	45..308	CDD:270787	103/272 (38%)
AT4G10730	NP_192811.4	S_TKc	47..308	CDD:214567	103/272 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910