DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment msn and Stk26

DIOPT Version :9

Sequence 1:	NP_524679.3	Gene:	msn / 44030	FlyBaseID:	FBgn0010909	Length:	1504	Species:	Drosophila melanogaster
Sequence 2:	NP_598490.1	Gene:	Stk26 / 70415	MGIID:	1917665	Length:	416	Species:	Mus musculus

Alignment Length:	442	Identity:	165/442 - (37%)
Similarity:	241/442 - (54%)	Gaps:	57/442 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAHQQQQQLAPSVNCSLDDIDLTALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDV 65
            |||.......|.:.        ..:.||..:|..:|.:|.|::|:|:||...:|.|:.|||::|:
Mouse     1 MAHSPVAVQVPGMQ--------NNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDL 57

  Fly    66 --TEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTK 128
              .|||.|:|:.||.||.: .:...:..|||:::|.|      :||::|||.|.||..||:::
Mouse    58 EEAEDEIEDIQQEITVLSQ-CDSSYVTKYYGSYLKGS------KLWIIMEYLGGGSALDLLRA-- 113

  Fly   129 GQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRN 193
             ....|..||.:.:|||:||.||||.|.||||||..||||::..:|||.||||:.||..|..:||
Mouse   114 -GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRN 177

  Fly   194 TFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPP 258
            ||:|||:|||||||     ..:.||:::|:|||||||:|:|:.:||..|:||||.|||||:|:||
Mouse   178 TFVGTPFWMAPEVI-----QQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPP 237

  Fly   259 RLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRKQEK 323
            .|.. .::|.|..|||..|.||...||..:.||||.||...........:|   |||.|:.|.|
Mouse   238 TLIG-DFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTEL---IDRFKRWKAE- 297

  Fly   324 EREDYRYSGSDNDDDEPQLAGEHSSIVQAPGGD----TLRR--NFQQIQEGRLAAEQQQQHHLMA 382
                   ..||.:.|......|.||....|..:    |:|:  :.:::|.|    |:|.
Mouse   298 -------GHSDEESDSEGSDSESSSRESNPHPEWSFTTVRKKPDPKKLQNG----EEQD------ 345

  Fly   383 QAQAQAAAAHAAAQAQAQLQQQQQQAAAAAAAAAHAAQQAQQAAQQAQAQQP 434
            ..|..:..:.....|.|:|:||.:.    .|:...|.::.:::...|:...|
Mouse   346 LVQTLSCLSMIITPAFAELKQQDEN----NASRNQAIEELEKSIAVAETACP 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	129/272 (47%)
		S_TKc	32..296	CDD:214567	127/265 (48%)
		CNH	1183..1484	CDD:214481
Stk26	NP_598490.1	STKc_MST4	19..295	CDD:132971	136/294 (46%)
		S_TKc	24..274	CDD:214567	127/265 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	296..343		12/58 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910