Protein Alignment msn and Map4k5

DIOPT Version :9

• Sequence 1: NP_524679.3
• Gene: msn / 44030
• FlyBaseID: FBgn0010909
• Length: 1504
• Species: Drosophila melanogaster
• Sequence 2: NP_001178945.1
• Gene: Map4k5 / 503027
• RGDID: 1562028
• Length: 846
• Species: Rattus norvegicus
• Alignment Length: 686
• Identity: 205/686 - (29%)
• Similarity: 299/686 - (43%)
• Gaps: 198/686 - (28%)

  Fly    26 KDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTE-DEEEEIKLEINVLKKYSNHRNI 89
            ::|...:||::.||:||||.|||.|:..||:|||:|::.:.. |:...|:.||.::|: ..|.||
  Rat    14 RNPQHDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKE-CKHCNI 77

  Fly    90 ATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSN 154
            ..|:|:::.:      ::||:.|||||.||:.|:...|  ..|.|..|||:|||.|:||:|||:.
  Rat    78 VAYFGSYLSR------EKLWICMEYCGGGSLQDIYHVT--GPLSELQIAYVCRETLQGLAYLHTK 134

  Fly   155 KVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDN 219
            ..:||||||.|:||||:.:|||.||||:|::..||.:|.:||||||||||||.|.::|  ..|:.
  Rat   135 GKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKN--GGYNQ 197

  Fly   220 RSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNS--PPRLKSK-KWSKKFHGFIDTVLVKDY 281
            ..|:|::||||:|:.|.|||:.||||||||||:.:::  ||:||.| |||..||.|:...|.|:.
  Rat   198 LCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNP 262

  Fly   282 HQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRKQEKEREDYRYSGSDNDDDEPQLAGEH 346
            .:||..|.||.|.|:......|.:.::|.|.::......        .||..|:||.||.....|
  Rat   263 KKRPTAERLLTHTFVGQSGLSRALAVELLDKVNNPDNHA--------HYSEGDDDDFEPHAIIRH 319

  Fly   347 SSIVQAPGGDTLRRNFQQIQEGRLAAEQQQQHHLMAQAQAQAAAAHAAAQAQAQLQQQQQQAAAA 411
                      |:|
  Rat   320 ----------TIR---------------------------------------------------- 322

  Fly   412 AAAAAHAAQQAQQAAQQAQAQQPQANRQPKPPSRQQVE---EPGPPARPPQRLIVVPDPPHANR- 472
               :.:...:|::.|.:....:.|.    :||.|::.|   |.|..:.|...|...|....||.
  Rat   323 ---STNRNSRAERTASEINFDKLQF----EPPLRKETEARDEMGLSSEPNFILHWNPFVDGANTG 380

  Fly   473 ----------PLPPTPKCGE-PAGQTPQQQQRNSQNNFKPSLPPRRPEPQPQTAAGGQGSQQQAQ 526
                      ||||.|:... |....|.::        |.|...|.|:|:.:..   |..::|:.
  Rat   381 RSTSKRAIPPPLPPKPRINSYPEESLPDEE--------KSSTVKRCPDPETRAP---QVLRRQSS 434

  Fly   527 PEAPPRNNRQSSGLSSSGGSASGGGGSSKPAAALPQQSNNHLGQPVNPLDPLDSSDSDSEPDEPN 591
            |...|.....|.|         .|.|.||                      |.|.:::.....|.
  Rat   435 PSCVPIAETSSVG---------NGNGISK----------------------LISENTEGSAQAPQ 468

  Fly   592 DRARNDGTLLASDPPKP-LPGLGPVSE----------------DANTTTPLSHGSGGPPNRPLPP 639
            ...:.|    ..|.||| :.||.|..:                ..|..|...|
  Rat   469 LPRKKD----KRDFPKPTINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIH------------ 517

  Fly   640 TPDDDDQ-------AGDRTLIMKRKLEQNINRLQKS 668
             ||..||       .|..||        |:|.|.::
  Rat   518 -PDTKDQYIIFGTEDGIYTL--------NLNELHEA 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	131/273 (48%)
		S_TKc	32..296	CDD:214567	130/267 (49%)
		CNH	1183..1484	CDD:214481
Map4k5	NP_001178945.1	STKc_MAP4K5	10..277	CDD:270813	131/273 (48%)
		S_TKc	20..277	CDD:214567	130/267 (49%)
		CNH	511..826	CDD:214481	12/55 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910