DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment msn and Myo3a

DIOPT Version :9

Sequence 1:	NP_524679.3	Gene:	msn / 44030	FlyBaseID:	FBgn0010909	Length:	1504	Species:	Drosophila melanogaster
Sequence 2:	XP_574090.6	Gene:	Myo3a / 498806	RGDID:	1560083	Length:	268	Species:	Rattus norvegicus

Alignment Length:	240	Identity:	128/240 - (53%)
Similarity:	168/240 - (70%)	Gaps:	3/240 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 DPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIAT 91
            ||:..:|:.|.:|.||||:|:|..:.|.||.||:|::|...|.:|||:.|.|:|:..|:|.|:..
  Rat    16 DPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILRTLSDHPNVVR 80

  Fly    92 YYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKS--TKGQSLKEEWIAYICREILRGLSYLHSN 154
            :||.:.||... ..|:||||:|.|..||||||||.  .:|:.:.|..||||..|.|.||.:||||
  Rat    81 FYGIYFKKDKI-NGDKLWLVLELCNGGSVTDLVKGFLKRGERMSEPIIAYILHEALMGLQHLHSN 144

  Fly   155 KVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDN 219
            |.||||:||.|:|||....||||||||||||..|..|.||.:|||:|||||||||::..|.|||.
  Rat   145 KTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSSTRHRLNTSVGTPFWMAPEVIACEQQLDTTYDA 209

  Fly   220 RSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKK 264
            |.|.|||||||:|:.:..|||.:||||||||.|||:...:::.::
  Rat   210 RCDTWSLGITAIELGDGDPPLAELHPMRALFKIPRSGDQQVQDQQ 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	128/240 (53%)
		S_TKc	32..296	CDD:214567	126/235 (54%)
		CNH	1183..1484	CDD:214481
Myo3a	XP_574090.6	PKc_like	2..258	CDD:419665	128/240 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910