Protein Alignment msn and Myo3a

DIOPT Version :10

• Sequence 1: NP_524679.3
• Gene: msn / 44030
• FlyBaseID: FBgn0010909
• Length: 1504
• Species: Drosophila melanogaster
• Sequence 2: NP_001406660.1
• Gene: Myo3a / 498806
• RGDID: 1560083
• Length: 1614
• Species: Rattus norvegicus
• Alignment Length: 307
• Identity: 157/307 - (51%)
• Similarity: 206/307 - (67%)
• Gaps: 11/307 - (3%)

  Fly    27 DPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIAT 91
            ||:..:|:.|.:|.||||:|:|..:.|.||.||:|::|...|.:|||:.|.|:|:..|:|.|:..
  Rat    16 DPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILRTLSDHPNVVR 80

  Fly    92 YYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKS--TKGQSLKEEWIAYICREILRGLSYLHSN 154
            :||.:.||... ..|:||||:|.|..||||||||.  .:|:.:.|..||||..|.|.||.:||||
  Rat    81 FYGIYFKKDKI-NGDKLWLVLELCNGGSVTDLVKGFLKRGERMSEPIIAYILHEALMGLQHLHSN 144

  Fly   155 KVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDN 219
            |.||||:||.|:|||....||||||||||||..|..|.||.:|||:|||||||||::..|.|||.
  Rat   145 KTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSSTRHRLNTSVGTPFWMAPEVIACEQQLDTTYDA 209

  Fly   220 RSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKK-WSKKFHGFIDTVLVKDYHQ 283
            |.|.|||||||:|:.:..|||.:||||||||.||||.||:|:..: ||.:|:.||...|.|||.:
  Rat   210 RCDTWSLGITAIELGDGDPPLAELHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEK 274

  Fly   284 RPYTENLLKHGFIKD-QPTDRQVRIQLKDHID--RC----KKRKQEK 323
            ||...:||||.||.. :..|..::.||.:.||  :|    :|.:.|:
  Rat   275 RPTVSDLLKHKFITQIEGRDAILQKQLMEFIDIHQCLGSTEKARHER 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	147/271 (54%)
		CNH	1183..1484	CDD:214481
Myo3a	NP_001406660.1	Protein Kinases, catalytic domain	2..287	CDD:473864	147/271 (54%)
		MYSc_Myo3	352..1040	CDD:276830
		MBD_Myo3a	1408..1455	CDD:439318