DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment msn and fray

DIOPT Version :9

Sequence 1:	NP_524679.3	Gene:	msn / 44030	FlyBaseID:	FBgn0010909	Length:	1504	Species:	Drosophila melanogaster
Sequence 2:	NP_001303449.2	Gene:	fray / 44233	FlyBaseID:	FBgn0023083	Length:	707	Species:	Drosophila melanogaster

Alignment Length:	457	Identity:	132/457 - (28%)
Similarity:	192/457 - (42%)	Gaps:	116/457 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 FELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTE--DEEEEIKLEINVLKKYSNHRNIATYYG 94
            :||.:|:|.|....|:........:..|||.:::.:  ...:|:..||..:.. ..|.|:.||:.
  Fly   193 YELRDVIGVGATAVVHGAYCIPRNEKCAIKRINLEKWNTSMDELLKEIQAMSS-CFHENVVTYHT 256

  Fly    95 AFIKKSPPGKDDQLWLVMEYCGAGSVTDLVK------STKGQSLKEEWIAYICREILRGLSYLHS 153
            :|:.:      ::||||:.....||:.|::|      :.|.....|..||.:.:|:|:||.|.||
  Fly   257 SFVVR------EELWLVLRLLEGGSLLDIIKHKMRTSNCKQGVFDEATIATVLKEVLKGLEYFHS 315

  Fly   154 NKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQL--DRTIGR---RNTFIGTPYWMAPEVIACDENP 213
            |..||||||..|:|:.|:..:::.||||||.|  .|.:.|   |:||:|||.||||||:..|..
  Fly   316 NGQIHRDIKAGNILIGDDGTIQIADFGVSAWLATGRDLSRQKVRHTFVGTPCWMAPEVMEQDHG- 379

  Fly   214 DATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKS--------KKWSKKFH 270
               ||.::|:||.||||:|||....|.....||:.|.|..:|.||.|.:        |.:.|.|.
  Fly   380 ---YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFR 441

  Fly   271 GFIDTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQ--------LKDHIDRCKKRKQ------ 321
            ..|...|.|:..:||....||||.|.| :..||:...|        ::..:.:..||:.
  Fly   442 KMIVECLQKEPSKRPTASELLKHAFFK-KAKDRKYLTQTLLQSGPSMETRVHKAAKRQPGASGRL 505

  Fly   322 ----------EKERED------------------------------YRYSGSDNDDDE--PQLAG 344
                      ..|.||                              .|...||:|.:|  |::..
  Fly   506 HRTVTGEWVWSSEEEDNGGSATGSGTGDRKHPSSDSDSEDRPMNRLERADSSDSDREEPSPEITH 570

  Fly   345 EHSSIVQAPGGDTLRRNFQQIQEGRLAAEQQQQHHLMAQAQAQAAAAHAAAQAQAQLQQQQQQAA 409
            ..||....||                           |.|.|.|.||.......|||....:.|.
  Fly   571 SVSSATVTPG---------------------------APAAAGAGAAQELTAGIAQLPLPSEAAG 608

  Fly   410 AA 411
            .|
  Fly   609 EA 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	101/284 (36%)
		S_TKc	32..296	CDD:214567	101/284 (36%)
		CNH	1183..1484	CDD:214481
fray	NP_001303449.2	STKc_OSR1_SPAK	191..467	CDD:270787	101/284 (36%)
fray	NP_001303449.2	OSR1_C	613..670	CDD:403428
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438565
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840