DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment msn and stk24b

DIOPT Version :9

Sequence 1:	NP_524679.3	Gene:	msn / 44030	FlyBaseID:	FBgn0010909	Length:	1504	Species:	Drosophila melanogaster
Sequence 2:	XP_005165890.1	Gene:	stk24b / 406786	ZFINID:	ZDB-GENE-040426-2841	Length:	432	Species:	Danio rerio

Alignment Length:	452	Identity:	172/452 - (38%)
Similarity:	250/452 - (55%)	Gaps:	66/452 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAHQQQQQLAPSVNCSLDDIDLTALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDV 65
            |||...|...|.:.      :|.|  ||..:|..:|.:|.|::|:|:||...:|.::.|||::|:
Zfish     1 MAHSPVQGSLPGMQ------NLKA--DPEELFTKLERIGKGSFGEVFKGIDNRTQKVVAIKIIDL 57

  Fly    66 --TEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTK 128
              .|||.|:|:.||.||.: .:...:..|||:::      ||.:||::|||.|.||..||::.
Zfish    58 EEAEDEIEDIQQEITVLSQ-CDSPFVTKYYGSYL------KDTKLWIIMEYLGGGSALDLLEP-- 113

  Fly   129 GQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRN 193
             .||.|..||.|.||||:||.||||.|.||||||..||||::..||||.||||:.||..|..:||
Zfish   114 -GSLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIKRN 177

  Fly   194 TFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPP 258
            ||:|||:|||||||     ..:.||:::|:|||||||:|:|:.:||..|||||:.|||||:|:||
Zfish   178 TFVGTPFWMAPEVI-----KQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPP 237

  Fly   259 RLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRI-----QLKDHIDRCKK 318
            .|:. .:.|....|::..|.|:...||..:.||||..|        ||.     .|.:.||:.|:
Zfish   238 TLEG-NYCKPLKEFVEACLNKEPSFRPTAKELLKHKLI--------VRFAKKTSYLTELIDKYKR 293

  Fly   319 RKQEKEREDYRYSGSDNDDDEPQLAGEHSSIVQAPGGD---------TLR-RNFQQIQEG-RLAA 372
            .|.|:.|.:   |.||..|.||.        .||.||:         |:| ::.:::|.| .|..
Zfish   294 WKAEQSRAE---SSSDESDSEPD--------GQASGGNDFGNDDWIFTIREKDPKKLQNGASLVG 347

  Fly   373 EQQQQHHLMAQAQAQAAAAHAAAQAQAQLQQQQQQAAAAAAAAAHAAQQAQQAAQQAQAQQP 434
            |::.....::|     :.:........:|::...:||||........:|..:|...|:...|
Zfish   348 EEEPNKRPLSQ-----SLSTVITPVLTELKEGAGEAAAATTVKPEVLEQLGEAIFLAEEAYP 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	129/272 (47%)
		S_TKc	32..296	CDD:214567	127/265 (48%)
		CNH	1183..1484	CDD:214481
stk24b	XP_005165890.1	STKc_MST3_like	22..295	CDD:270786	134/296 (45%)
stk24b	XP_005165890.1	S_TKc	24..274	CDD:214567	127/265 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910