DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment msn and myo3a

DIOPT Version :9

Sequence 1:	NP_524679.3	Gene:	msn / 44030	FlyBaseID:	FBgn0010909	Length:	1504	Species:	Drosophila melanogaster
Sequence 2:	NP_991142.2	Gene:	myo3a / 402814	ZFINID:	ZDB-GENE-041026-4	Length:	1775	Species:	Danio rerio

Alignment Length:	343	Identity:	161/343 - (46%)
Similarity:	210/343 - (61%)	Gaps:	28/343 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 DPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIAT 91
            ||:..:|:||.:|.||||:|||..:...|..||:|::|...|.:|||:.|.|:||..|:|.|:..
Zfish    16 DPSDTWEIIETIGKGTYGKVYKVHNKVDGSKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVVK 80

  Fly    92 YYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKS--TKGQSLKEEWIAYICREILRGLSYLHSN 154
            ::|.|.||... ..||||||:|.|..||||||.|.  .:|..::|..||:|..|.|.||.:||.|
Zfish    81 FFGMFYKKDVK-TGDQLWLVLELCNGGSVTDLAKGMLKRGDRMEEPIIAFILHEALMGLQHLHVN 144

  Fly   155 KVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDN 219
            |.||||:||.|:|||.:..:|||||||||||..|..||||.:|||:|||||||||::..|:|||.
Zfish   145 KTIHRDVKGNNILLTTDGGIKLVDFGVSAQLTNTRLRRNTSVGTPFWMAPEVIACEQQLDSTYDE 209

  Fly   220 RSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRL-KSKKWSKKFHGFIDTVLVKDYHQ 283
            |.|:|||||||:|:.:..|||.:||||||||.||||.||.| :.:.||..|:.||...|:||:..
Zfish   210 RCDVWSLGITAIELGDGDPPLAELHPMRALFKIPRNPPPTLHQPELWSNDFNDFIRKCLIKDFEL 274

  Fly   284 RPYTENLLKHGFIKDQPTDRQVRIQ--------------------LKDHIDRCKKRKQEK---ER 325
            ||...:||:|.||| |...|:..:|                    |....||....:.|:   ::
Zfish   275 RPNVLDLLQHVFIK-QIVGREKTLQKQLMELIDLNQQMGIIEKTSLLGKSDRDSDSRHERIHTKK 338

  Fly   326 EDYRYSGSDNDDDEPQLA 343
            ..|..|.|...||...||
Zfish   339 NSYMKSQSQTCDDADDLA 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	144/271 (53%)
		S_TKc	32..296	CDD:214567	142/266 (53%)
		CNH	1183..1484	CDD:214481
myo3a	NP_991142.2	PKc_like	2..287	CDD:328722	144/271 (53%)
myo3a	NP_991142.2	MYSc_Myo3	364..1091	CDD:276830
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810