DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment msn and Myo3b

DIOPT Version :9

Sequence 1:	NP_524679.3	Gene:	msn / 44030	FlyBaseID:	FBgn0010909	Length:	1504	Species:	Drosophila melanogaster
Sequence 2:	NP_001380706.1	Gene:	Myo3b / 366069	RGDID:	1560313	Length:	1333	Species:	Rattus norvegicus

Alignment Length:	281	Identity:	139/281 - (49%)
Similarity:	189/281 - (67%)	Gaps:	8/281 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LTALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNH 86
            |.:|.||...:|:.|.:|.||||:|||..:.:.|.|||:|::|...|.:||::.|.|:|:...:|
  Rat    33 LESLPDPMDTWEIRETIGKGTYGKVYKVANRRDGSLAAVKILDSVNDVDEEVEAEYNILQFLPSH 97

  Fly    87 RNIATYYGAFIK--KSPPGKDDQLWLVMEYCGAGSVTDLVKSTK--GQSLKEEWIAYICREILRG 147
            .|:..:||.|.|  :...|   |||||:|.|..||||:|||...  |:.|.|..|:||....|.|
  Rat    98 PNVVKFYGMFYKADRCVGG---QLWLVLELCNGGSVTELVKGLLRCGKRLDEALISYILYGSLLG 159

  Fly   148 LSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDEN 212
            |.:||.:::||||:||.|:|||....||||||||||||..|..||||.:|||:|||||||||::.
  Rat   160 LQHLHHHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQ 224

  Fly   213 PDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPR-LKSKKWSKKFHGFIDTV 276
            .|::||.|.|:|||||||:|:.:..|||.::||::.||.||||.||. |....|.::|:.||...
  Rat   225 YDSSYDARCDVWSLGITAIELGDGDPPLFEMHPVKMLFKIPRNPPPTLLHPDNWCEEFNHFISQC 289

  Fly   277 LVKDYHQRPYTENLLKHGFIK 297
            |:||:.:||...:||.|.|||
  Rat   290 LIKDFEKRPSVTHLLDHPFIK 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	135/275 (49%)
		S_TKc	32..296	CDD:214567	132/268 (49%)
		CNH	1183..1484	CDD:214481
Myo3b	NP_001380706.1	MYSc_Myo3	373..1062	CDD:276830
		IQ	1102..1124	CDD:197470
		PKc_like	20..310	CDD:419665	137/279 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000