Protein Alignment msn and Nrk

DIOPT Version :9

• Sequence 1: NP_524679.3
• Gene: msn / 44030
• FlyBaseID: FBgn0010909
• Length: 1504
• Species: Drosophila melanogaster
• Sequence 2: XP_006528613.1
• Gene: Nrk / 27206
• MGIID: 1351326
• Length: 1512
• Species: Mus musculus
• Alignment Length: 1696
• Identity: 486/1696 - (28%)
• Similarity: 725/1696 - (42%)
• Gaps: 425/1696 - (25%)

  Fly    21 DLTALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTE------------------ 67
            ||..|.||.|||.|.:.:|.||||:::.|.|.|||.|.|:|||...:
Mouse    14 DLGQLPDPTGIFSLDKAIGLGTYGRIFLGIHEKTGSLVAVKVMSARKTPLPEIGRRVRVNKYQKS 78

  Fly    68 ------DEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKS 126
                  ||||:::.|:|:|:|||.|:||.|:||||.|.:|||...|||:|||.|.||||||:|:.
Mouse    79 VGWRYSDEEEDLRTELNLLRKYSFHKNIVTFYGAFFKLNPPGHQHQLWMVMELCAAGSVTDVVRM 143

  Fly   127 TKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGR 191
            |:.|||||:||||||||||:||::||:::||||||||||||||.:||||:||||||||:.||.||
Mouse   144 TRNQSLKEDWIAYICREILQGLAHLHAHQVIHRDIKGQNVLLTHDAEVKIVDFGVSAQVSRTNGR 208

  Fly   192 RNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNS 256
            ||:|||||||||||||.|||:|..:||.|||:||:||||:||||..||||.|.|:.||.:|.|.:
Mouse   209 RNSFIGTPYWMAPEVIHCDEDPRCSYDYRSDVWSVGITAIEMAEGAPPLCKLQPLEALCVILREA 273

  Fly   257 PPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRKQ 321
            .|::||..||:||..|::..::|::..||.:.|:|.|.|:.|...:|:|...|..|:....::::
Mouse   274 APKVKSSGWSRKFQNFMENCMIKNFLFRPTSGNMLLHPFVHDIKNERRVVESLTKHLTGIIQKRE 338

  Fly   322 EK-----------EREDY---RYSGSDNDDDEPQLAGEHSSIVQAPGGDTLRRNFQQIQEGRLAA 372
            :|           .:|.|   |:.|       |....|...:..:.....||....:..:.|...
Mouse   339 KKGIPVAFEGEEAAKEQYITRRFRG-------PSCTPELLRVPTSSRCRPLRVLHGEPPQPRWLP 396

  Fly   373 EQQQQHHLMAQAQAQAAAAHAAAQAQ---AQLQQQQQQAAAAAAAAA----------HAAQQAQQ 424
            :|:.......|...:||.......:|   ::|..:|.:.|.....||          .|..|..:
Mouse   397 DQEDPQDQELQQLQKAAGVFMPLHSQDNTSKLFPKQVEVAPYLRGAAQVVMPVLVQVEAPPQVSK 461

  Fly   425 AAQQAQAQQPQANRQPKPPSR------QQVEEPGPPARPPQRLIVVPDPPHANRPLPPTPKCGEP 483
            |||..::...|.|:...|..:      ||.:........|:.|..||:........|..|:
Mouse   462 AAQMLKSLPTQDNKATSPEVQAPVAEGQQAQHEALETEQPKDLDQVPEEFQGQDRAPEQPR---- 522

  Fly   484 AGQTPQQQQRNSQNNFKPSLPP---RRPEPQPQTAAGGQGSQQQAQPEA--PPRNNRQSSGLSSS 543
            .||..:|||   .:|..|..||   |.||            |.:.|.||  ||:...:
Mouse   523 QGQAAEQQQ---IHNPVPEQPPEEDREPE------------QAEVQEEAVEPPQAEIE------- 565

  Fly   544 GGSASGGGGSSKPAAA-------LPQQS-NNHLGQPVNPLD-----PLDSSDSDSEPDEPNDRA- 594
                     ..:|...       ||..| |.|:..|:: ||     |:      .|.:|...||
Mouse   566 ---------DKEPEVVQVHAQVLLPLLSQNRHVLLPLH-LDRQLLIPV------GEQNEEVPRAQ 614

  Fly   595 -------RNDGTLLASDPPKPLPGLGPVSED------ANTTTPL--------SHGSGGPPNRPLP 638
                   |..|.:.|.     :.||   |.|      |..|.||        :..:.|....|.|
Mouse   615 AWDLEASRAVGAVQAL-----IEGL---SRDLLRAPNAFVTKPLGPLQIFLENLSTDGFYTEPEP 671

  Fly   639 PTPDDDDQAGDRTLIMKRKLEQNIN-----RLQ----KSASTS-----------------QANVT 677
            ........|..|..|.||...:...     ||:    ....||                 |....
Mouse   672 TQKKKSKVASLRKAIAKRLRPKRFRAKALWRLEDFEFSDVETSRRRRHRRWEDIFNQHEEQLRRV 736

  Fly   678 PSRRGDESNLLRDWDFDRFF----------PKNANGPRGS---GRGSPTTTASLSRSSQLSTLKV 729
            .:.|.|:|:     |.|..|          |..|| |.|:   .|.:| ...:.:|:.::. ...
Mouse   737 ENDREDDSS-----DNDEVFHSIQAEVQIEPHAAN-PAGNEVHERSAP-MPCNRNRTHRVK-FSP 793

  Fly   730 DTKLQRASVAEAITRPVPRGYQPLKAEPSASQSIAKEQGSASGSGSGSGSASGSGSGGSTNSPAH 794
            ....:..|:.||  :|..:..||:...|   ::....|...:.|.|.|...|......|.:||.:
Mouse   794 SVGEEEPSLEEA--QPQQQQQQPMNIRP---RNCLNPQNFQAQSDSSSEEDSPVTRRKSQSSPPY 853

  Fly   795 KRQDS----DSRLPTNFERGFRRENSDFFPLAKRYSAVFSGASASGSTAGSPSAQALQRSSAVYQ 855
            ...|.    |..:|..|:.|                                     :.|..||.
Mouse   854 STIDQKLLIDIHVPDGFKVG-------------------------------------KISPPVYL 881

  Fly   856 RNSIYSSSISSKSKEND--VPGAPGAAAAGTATASAKPGPAAATTTATKGAAPKTSKSLANFHFL 918
            .|.....:..|:...:|  :|..|       |....:.|.......|...|  ...:.:||..:.
Mouse   882 TNEWVGYNALSEIFWDDWIMPTRP-------ARPPEEDGDYVELYDADANA--NGDEEVANGAYE 937

  Fly   919 RPRREKTESVIVLQNAAVRAQRLQQLQQQQQQQQLQQQQQQQN--RGGGGGGGGGGGGGGSSGVG 981
            .||                       ........:..|..|.|  .|.|..|..||..||:.|..
Mouse   938 DPR-----------------------DGANGHDDMNNQLDQANGYEGHGAAGYNGGDVGGNHGAA 979

  Fly   982 ADGTGLGTPGTRTSSVLPDLLSQASPATPPRHDKSSSEEYQAAISSSVHS--------------- 1031
            .:|.....|                               :|.|..:.|:
Mouse   980 FNGPRANYP-------------------------------RAGILKNGHNDGRALNRGAFGVFGD 1013

  Fly  1032 TPSKSFIASSGSGGLGLGGGTVVGGVIISSNHSPQSTISLASSSSNSRQNSPKNSISKTRSSSSI 1096
            ..:::|..::|..|...|            ||        .::..|.|.|..:.:..:...:.:.
Mouse  1014 NAARAFHGAAGEAGAAFG------------NH--------GANRGNGRGNRNREANGRNEENGAF 1058

  Fly  1097 TNLLHKSASSSSANLHHLTPCSSTSSASISNPLPPHAYALQQ---KQRSFLTFGFGAGGSGPSRR 1158
            ....|......    |..:...:.:|.||:  |...::..:|   :..|..|.||..|.|.|...
Mouse  1059 GRDQHVFPEFE----HEESDRGTETSDSIA--LEITSFDGEQNSGRPVSSTTMGFPIGRSSPRGS 1117

  Fly  1159 E--SHVNVNVTPTSHEAANDTPEIRKYKKRFNSEILCAALWGVNLLIGTENGLMLLDRSGQGKVY 1221
            :  |.::.|           :|.:..|:|.|:||:.|.:|||||||:||::.|.|:||||:.::.
Mouse  1118 DFGSDISYN-----------SPILHVYEKDFSSEVYCGSLWGVNLLLGTQSHLYLMDRSGKAEIV 1171

  Fly  1222 QLISRRRFQQMEVLEGQNILVTISGKKNRVRVYYLSWLKSKILRTDGLSDQVE-----RRNGWIN 1281
            :||.||.|:|::|:|..|:|:||||||||:|||:||||::|||..|..|.:.:     :......
Mouse  1172 KLIKRRPFRQIQVVEQLNLLITISGKKNRLRVYHLSWLRNKILNNDPKSKKRQKAMRKKEEACKA 1236

  Fly  1282 VGDLQGAVHFKIVKYERIKFLVIALKDSIEIYAWAPKPYHKFMA--------------------- 1325
            :..|.|..||.::::|...::.:|:|.||.::|||||.:.:..|
Mouse  1237 IDKLIGCEHFSVLQHEETTYIAVAVKSSIHLFAWAPKSFDENTAIKVLCIDQSADSEGDYMSYEA 1301

  Fly  1326 ----------------FKNFGELEH------------RPLLVDLTIEDQSRLKVIYGSAEGFHAV 1362
                            ||...||.|            :||.|||.:..:..||:.:.||.|:|.:
Mouse  1302 YIRILAKIQAADPANRFKRPDELLHLLKLKVFPTRDLKPLTVDLAVGSEKTLKIFFSSANGYHII 1366

  Fly  1363 DLDSAEVYDIYLPKHTQGAIIPHCIVALPNSNGMQLLLCYDNEGVYVNTVGRVSKNIVLQWGEMP 1427
            |.:|..:.::.||.::...|||..:|.||:..|:.::|..:.|........::.|.|:..|.::|
Mouse  1367 DAESEVMSEVTLPNNSLEIIIPQNVVILPDCLGLGVMLSLNAEAASEEANEQLLKKILDVWKDIP 1431

  Fly  1428 TSVAYIGTGQIMGWGNKAIEIRSVESGHLDGVFMHKKAQRLKFLCERNDKVFFSSAKGASSCQIY 1492
            :|||:..|.:|.||..||||:||::|..|:.....:..::|:|||.|.||:||:|.......::|
Mouse  1432 SSVAFECTKRITGWDQKAIEVRSLQSTILENELKRRSIKKLRFLCARGDKMFFASTLSNDHSRVY 1496

  Fly  1493 FMTLNK 1498
            .|:|.|
Mouse  1497 LMSLGK 1502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	166/294 (56%)
		S_TKc	32..296	CDD:214567	161/287 (56%)
		CNH	1183..1484	CDD:214481	124/354 (35%)
Nrk	XP_006528613.1	PKc_like	14..313	CDD:389743	168/298 (56%)
		rne	<430..578	CDD:236766	39/182 (21%)
		CNH	1143..1479	CDD:382970	113/335 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D246443at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48015
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020