DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment msn and sid1

DIOPT Version :9

Sequence 1:	NP_524679.3	Gene:	msn / 44030	FlyBaseID:	FBgn0010909	Length:	1504	Species:	Drosophila melanogaster
Sequence 2:	NP_593564.1	Gene:	sid1 / 2542746	PomBaseID:	SPAC9G1.09	Length:	471	Species:	Schizosaccharomyces pombe

Alignment Length:	348	Identity:	128/348 - (36%)
Similarity:	188/348 - (54%)	Gaps:	44/348 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 AGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTE--DEEEEIKLEINVLKKYSNHRNIAT 91
            |..:.|:..:|:|::|.|:|.|...:|.:.|||.:|:..  |:..:|:.|:.:|.. .|..|:..
pombe     6 ANSYTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLSN-CNSSNVIQ 69

  Fly    92 YYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKV 156
            |||.|:      ....||::||:...|||:.|:|..:   |.|:.|:.|.||:|.||:|||....
pombe    70 YYGCFV------DGYTLWILMEHMDGGSVSGLLKMGR---LNEQVISIILREVLYGLNYLHGQNK 125

  Fly   157 IHRDIKGQNVLLTDN-AEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNR 220
            ||||||..|:||:.: ..|||.||||:|||.....||:||:|||:|||||||     ...:|...
pombe   126 IHRDIKAANILLSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVI-----QQTSYGLA 185

  Fly   221 SDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKKWSKKFHGFIDTVLVKDYHQRP 285
            :|:|||||||:|||...||...:||||.:|.||::.||:| ...:|..|..|:...|..:.:.|.
pombe   186 ADIWSLGITAIEMANGIPPRATMHPMRVIFEIPQSEPPKL-DDHFSPTFRDFVSCCLDLNPNMRW 249

  Fly   286 YTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRKQEKEREDYRYSGSDNDDDEPQLAGEHSSIV 350
            ..:.||:|.|||...|       :||.|...    .:||.:.:        ||..|      |::
pombe   250 SAKELLQHPFIKSAGT-------VKDIIPLL----VQKENKLF--------DDSDQ------SVL 289

  Fly   351 QAPGGDTLRRNFQQIQEGRLAAE 373
            :....:||:...:.|.||....|
pombe   290 EETINNTLKPFEEPIAEGNADIE 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	109/269 (41%)
		S_TKc	32..296	CDD:214567	108/266 (41%)
		CNH	1183..1484	CDD:214481
sid1	NP_593564.1	STKc_MST3_like	7..279	CDD:270786	117/298 (39%)
sid1	NP_593564.1	S_TKc	9..260	CDD:214567	108/266 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910