DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment msn and ppk11

DIOPT Version :9

Sequence 1:	NP_524679.3	Gene:	msn / 44030	FlyBaseID:	FBgn0010909	Length:	1504	Species:	Drosophila melanogaster
Sequence 2:	NP_594517.1	Gene:	ppk11 / 2541473	PomBaseID:	SPAC2C4.14c	Length:	312	Species:	Schizosaccharomyces pombe

Alignment Length:	265	Identity:	105/265 - (39%)
Similarity:	158/265 - (59%)	Gaps:	16/265 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 IEVVGNGTYGQVYKGRHTKTGQLAAIKV--MDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFI 97
            ::::|.|::|.|::.:..::.::.|:||  :|.|:|:.|.:..|||.|... |..:|..||.:|:
pombe     9 LQLIGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQEINFLIDL-NSVHITKYYASFV 72

  Fly    98 KKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIK 162
                  ...:||:.||||..||..||:|.:  .:..|..||.:.|::|..|.|||....:|||||
pombe    73 ------DGFRLWITMEYCDGGSCLDLLKLS--GTFSERVIAEVMRQVLEALVYLHGQGKMHRDIK 129

  Fly   163 GQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLG 227
            ..|:|...:..|||.|||||.||:....:.:.|:|||:||||||:     ....|:.::|:||||
pombe   130 AANILTMKDGLVKLADFGVSGQLESLRDKNDDFVGTPFWMAPEVV-----KQTGYNYKADIWSLG 189

  Fly   228 ITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLK 292
            |||.|:|..:||...:|||:.|.|||::|||.|:..|:|:.|..|:...|.|:...|...|.|.|
pombe   190 ITAYELATGEPPYSGIHPMKVLLLIPKHSPPSLERSKFSRAFCDFVSNCLKKNPKDRATAEYLSK 254

  Fly   293 HGFIK 297
            |.|||
pombe   255 HKFIK 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	102/262 (39%)
		S_TKc	32..296	CDD:214567	102/262 (39%)
		CNH	1183..1484	CDD:214481
ppk11	NP_594517.1	STKc_MST3_like	4..278	CDD:270786	105/265 (40%)
ppk11	NP_594517.1	S_TKc	6..258	CDD:214567	102/262 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910