Protein Alignment msn and map4k4

DIOPT Version :9

• Sequence 1: NP_524679.3
• Gene: msn / 44030
• FlyBaseID: FBgn0010909
• Length: 1504
• Species: Drosophila melanogaster
• Sequence 2: XP_021334466.1
• Gene: map4k4 / 103908625
• ZFINID: ZDB-GENE-030131-6722
• Length: 1006
• Species: Danio rerio
• Alignment Length: 1414
• Identity: 571/1414 - (40%)
• Similarity: 726/1414 - (51%)
• Gaps: 429/1414 - (30%)

  Fly   112 MEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKL 176
            ||:|||||:|||||:|||.:|||:|||||.|||||||::||::.||||||||||||||:||||||
Zfish     1 MEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHAHHVIHRDIKGQNVLLTENAEVKL 65

  Fly   177 VDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITALEMAESQPPLC 241
            ||||||||||||:|||||||||||||||||||||||||||||.||||||.||||:||||..||||
Zfish    66 VDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLC 130

  Fly   242 DLHPMRALFLIPRNSPPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVR 306
            |:||||||||||||.|||||||||||||..||:..|||:|.|||.|:.||||.||:|||.:||||
Zfish   131 DMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYTQRPPTDQLLKHPFIRDQPNERQVR 195

  Fly   307 IQLKDHIDRCKKRKQEKEREDYRYSGSDNDDDEPQ-LAGEHSSIVQAPGGDTLRRNFQQI-QEGR 369
            ||||||:|||:|::.||:..:|.||||:.:::|.| ..||.||||..||..||||:|.:: ||.:
Zfish   196 IQLKDHLDRCRKKRGEKDETEYEYSGSEEEEEESQEQEGEPSSIVNVPGESTLRRDFIRLQQENK 260

  Fly   370 LAAEQQQQHHLMAQAQAQAAAAH---AAAQAQAQLQQQQQQAAAAAAAAAHAAQ-QAQQAAQQAQ 430
            ..:|..::..|:.:.|.:....:   ..|:.|.:::||::|............: :.||..:|.:
Zfish   261 ERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREMRRQQEREQRR 325

  Fly   431 AQQPQANRQPKPPSRQQVEEPGPPARPPQRLIVVPDPPHANRPLPPTPKCGEPAGQ--------- 486
            .:|.:..|..:...|::.||....|...:|. ...:..:..|.|....:..|...|
Zfish   326 REQEEKRRVEELERRRKEEEERRRAEEEKRR-ADREQEYIRRQLEEEQRHLEILQQQLLHEQAML 389

  Fly   487 -TPQQQQRNSQNNFKPSLPPRRPEPQPQTAAGGQGSQQQAQPEAPPRNNRQSSGLSSSGGSASGG 550
             ..::.:||.|.:             ||.|.     .|:..|..|||.:.     ..|.||||
Zfish   390 LVDERHRRNVQGS-------------PQAAV-----LQKQPPAVPPRASE-----PFSNGSAS-- 429

  Fly   551 GGSSKPAAALPQQSNNHLGQPVNPLDPLDSSDSDSEPDEPNDRARNDGTLLASDPPKPLPGLGPV 615
                       :||:                    ...||.|.......|.|.:..:|
Zfish   430 -----------EQSH--------------------RAPEPQDLTALAKELRAVEDVRP------- 456

  Fly   616 SEDANTTTPLSHGSGGPPNRPLPPTPDDDDQAGDRTLIMKRKLEQNINRLQKSASTSQANVTPSR 680
            ...|...:..|..||        .|.|:||:          ::||:|
Zfish   457 QHKATEYSSSSDDSG--------TTDDEDDE----------EVEQDI------------------ 485

  Fly   681 RGDESNLLRDWDFDRFFPKNANGPRGSGRGSPTTTASLSRSSQLSTLKVDTKLQRASVAEAITRP 745
             ||||               .:||..|..|          ||:||
Zfish   486 -GDES---------------TSGPEDSRGG----------SSRLS-------------------- 504

  Fly   746 VPRGYQPLKAEPSASQSIAKEQGSASGSGSGSGSASGSGSGGSTNSPAHKRQDSDSRLPTNFERG 810
                    ..|..||:::..                               ||.|
Zfish   505 --------NGETEASKTMVV-------------------------------QDDD---------- 520

  Fly   811 FRRENSDFFPLAKRYSAVFSGASASGSTAGSPSAQALQRSSAVYQRNSIYSSSISSKSKENDVPG 875
                                    |.||....|...:::    :||:
Zfish   521 ------------------------SSSTPCKDSTLVMRQ----FQRS------------------ 539

  Fly   876 APGAAAAGTATASAKPGPAAATTTATKGAAPKTSKSLANFHFLRPRREKTESVIVLQNAAVRAQR 940
                            ||   .|....|....:|:|               .|.::|.:.||.:
Zfish   540 ----------------GP---VTLLGSGWTDASSRS---------------PVEIVQRSCVRGR- 569

  Fly   941 LQQLQQQQQQQQLQQQQQQQNRGGGGGGGGGGGGGGSSGVGADGTGLGTPGTRTSSVLPDLLSQA 1005
                                                                  :.:|||||.|:
Zfish   570 ------------------------------------------------------NPLLPDLLQQS 580

  Fly  1006 SPATPPRHDKSSSEEYQAAISSSVHSTPSKSFIASSGSGGLGLGGGTVVGGVIISSNHSPQSTIS 1070
            ..|.||.....|               |::|.:            |....|..:|.:.:|
Zfish   581 PRAPPPLPSPCS---------------PARSPL------------GPPEPGPRLSLSETP----- 613

  Fly  1071 LASSSSNSRQNSPKNSISKTRSSSSIT-----NLLHKSASSSSANLHHLTPCSSTSSASISNPLP 1130
                           ::.|.:||||.|     .||..|.|:.||          .::|..||..
Zfish   614 ---------------TVPKHKSSSSFTPFIDPRLLQISPSTGSA----------LNNAGYSNDA- 652

  Fly  1131 PHAYALQQKQRSFLTFGFGAGGSGPSRRESHVNVNVTPTSHEAANDTPEIRKYKKRFNSEILCAA 1195
                .||:..|           ...||:.|.||||  |.:....|||||||||||||||||||||
Zfish   653 ----RLQEALR-----------QDASRKGSVVNVN--PVNTRPQNDTPEIRKYKKRFNSEILCAA 700

  Fly  1196 LWGVNLLIGTENGLMLLDRSGQGKVYQLISRRRFQQMEVLEGQNILVTISGKKNRVRVYYLSWLK 1260
            |||||||:|||:||||||||||||||.||:|||||||:||||.|:|||||||||::||||||||:
Zfish   701 LWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLR 765

  Fly  1261 SKILRTDGLSDQVERRNGWINVGDLQGAVHFKIVKYERIKFLVIALKDSIEIYAWAPKPYHKFMA 1325
            :|||..|   .:||::.||..||||:|.||:|:||||||||||:|||:|:|:|||||||||||||
Zfish   766 NKILHND---PEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVLALKNSVEVYAWAPKPYHKFMA 827

  Fly  1326 FKNFGELEHRPLLVDLTIEDQSRLKVIYGSAEGFHAVDLDSAEVYDIYLPKHTQGAIIPHCIVAL 1390
            ||:||:|.|:|||||||:|:..||||||||..||||||:||..|||||||.|.|.:|..|.|:.|
Zfish   828 FKSFGDLVHKPLLVDLTVEEGQRLKVIYGSCSGFHAVDVDSGAVYDIYLPTHIQTSIQSHAIIIL 892

  Fly  1391 PNSNGMQLLLCYDNEGVYVNTVGRVSKNIVLQWGEMPTSVAYIGTGQIMGWGNKAIEIRSVESGH 1455
            ||::|::||:||::|||||||.||::|::||||||||||||||.:.||||||.|||||||||:||
Zfish   893 PNTDGIELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQIMGWGEKAIEIRSVETGH 957

  Fly  1456 LDGVFMHKKAQRLKFLCERNDKVFFSSAKGASSCQIYFMTLNKPGMANW 1504
            ||||||||:||||||||||||||||:|.:...|.|:|||||.:..:.:|
Zfish   958 LDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW 1006

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	151/183 (83%)
		S_TKc	32..296	CDD:214567	151/183 (83%)
		CNH	1183..1484	CDD:214481	228/300 (76%)
map4k4	XP_021334466.1	PKc_like	<1..209	CDD:328722	170/207 (82%)
		CNH	688..986	CDD:214481	228/300 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	454	1.000	Domainoid score	I482
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46069
OrthoDB	1	1.010	-	-		D246443at33208
OrthoFinder	1	1.000	-	-		FOG0001422
OrthoInspector	1	1.000	-	-		otm24730
orthoMCL	1	0.900	-	-		OOG6_101812
Panther	1	1.100	-	-	O	PTHR48015
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X885
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.930