Protein Alignment msn and map4k4

DIOPT Version :9

• Sequence 1: NP_524679.3
• Gene: msn / 44030
• FlyBaseID: FBgn0010909
• Length: 1504
• Species: Drosophila melanogaster
• Sequence 2: XP_002934552.1
• Gene: map4k4 / 100491719
• XenbaseID: XB-GENE-1011650
• Length: 1403
• Species: Xenopus tropicalis
• Alignment Length: 1629
• Identity: 703/1629 - (43%)
• Similarity: 902/1629 - (55%)
• Gaps: 374/1629 - (22%)

  Fly    16 SLDDIDLTALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVL 80
            ||.||||::|:||||||||:||||||||||||||||.||||||||||||||||||||||||||:|
 Frog     9 SLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINML 73

  Fly    81 KKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREIL 145
            ||||:||||||||||||||||||.|||||||||:|||||:|||||:|||.||||:|||||.||||
 Frog    74 KKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNSLKEDWIAYISREIL 138

  Fly   146 RGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACD 210
            |||::||::.||||||||||||||:||||||||||||||||||:|||||||||||||||||||||
 Frog   139 RGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACD 203

  Fly   211 ENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKKWSKKFHGFIDT 275
            ||||||||.||||||.||||:||||..|||||:||||||||||||.|||||||||||||..||:.
 Frog   204 ENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEG 268

  Fly   276 VLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRKQEKEREDYRYSGSDNDDDE- 339
            .|||:|.|||.||.||||.||:|||.:|||||||||||||.:|::.||:..:|.||||:.:::|
 Frog   269 CLVKNYMQRPPTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEV 333

  Fly   340 PQLAGEHSSIVQAPGGDTLRRNF-----------------QQIQEGRLAAEQQQQHHLMAQAQAQ 387
            |:..||.||||..||..||||:|                 |.:||.:|..:::.:..|:|:.|.:
 Frog   334 PEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKR 398

  Fly   388 AAAAHAAAQAQAQLQQQQQQAAAAAAAAAHAAQQAQQAAQQAQAQQPQANRQPKPPSRQQVEEPG 452
               .....:.:.:|::||::...|         :.||..:|.:.:|.:..|..:...|::.||..
 Frog   399 ---IEQQKEQRRRLEEQQRREREA---------RRQQEREQRRREQEEKKRMEEMERRRKEEEER 451

  Fly   453 PPARPPQRLIVVPDPPHANRPLPPTPKCGEPAGQTPQQQQ------------------------- 492
            ..|...:|. |..:..:..|.|....:..|...|...|:|
 Frog   452 RRAEEEKRR-VEREQEYIRRQLEEEQRHLEILQQQLLQEQAMLLEYRWREMEEHRQAERLQRQLQ 515

  Fly   493 ------RNSQNNFKPSLPPRRPEPQPQTAAGGQGSQ-------QQAQP---------EAPPRNNR 535
                  .:.|::.:...||:: :||||.....|..:       |:.:|         ||..|..:
 Frog   516 QEQAYLMSLQHDHRQQQPPQQ-QPQPQQPPLSQQERSKQTYHTQEPKPHYEQAERIREAEERLRK 579

  Fly   536 QSSGLSSS--------------GGSASGGGGSSKPAAAL------PQQSNNHLGQPVNPLDPLDS 580
            .:.|...:              ..|.|...|:|:||...      ||...:||....|.:.|:..
 Frog   580 ANQGSPEAQAKQPGRVLEPLVPSRSESFSNGNSEPAQPAMHRPVEPQVQWSHLASLKNNVSPVSR 644

  Fly   581 SDSDSEP-----------DEPNDRARNDGTLLASDPPKPLPGLGPVSEDANTTTPLSHGSGGPPN 634
            |.|.|:|           .:.:..:|::.....|||.      ..:||........|.....||.
 Frog   645 SHSFSDPSPKFAPHLLRSQDSHQTSRSEVQSQGSDPK------SEISEPTQRVWARSDSDEVPPR 703

  Fly   635 RPLPPTPDDDDQAGDRTLIMKRKLEQNINRLQKSASTSQANVTPSRRGDESNLLRDWDFDRFFPK 699
            .|:..|        .|:.::.||                          :|.|
 Frog   704 VPVRTT--------SRSPVLSRK--------------------------DSPL------------ 722

  Fly   700 NANGPRGSGRGSPTTTASLSRSSQLSTLKVDTKLQRASVAEAITRPVPRGYQPLKAEPSASQSIA 764
                   .|.|...|.|    ..:.||..::.:|....|.:.:.||           .|.|.|.:
 Frog   723 -------QGSGQQNTQA----GQRNSTSNIEPRLLWERVEKLVPRP-----------GSGSSSGS 765

  Fly   765 KEQGSASGSGSGSGSASGS-----GSGGSTNSPAHKRQDSDSRLPTNFERGFRRENS----DFFP 820
            ...||.:||..||.|.||.     .|..|..||: :|.::.::.....:...|:..:    |...
 Frog   766 SNSGSQAGSHPGSQSGSGERFRMRSSSKSEGSPS-QRHENTAKKSEEKKEAVRQAKAPGEVDLTA 829

  Fly   821 LAKRYSAV-----------FSGAS-----------------ASGSTAGSPSAQALQRSSAVYQRN 857
            |||...||           :|.:|                 |..||:|...|:|:   |::...|
 Frog   830 LAKELRAVDDVRPLHKVTDYSSSSEESGTTDEEDDDMEQEGADESTSGPEDARAM---SSLNLSN 891

  Fly   858 SIYSSSISSKSKENDVPGAPGAAAAGTATASAKPGPAAATTTATKGAAPKTSKSLANFHFLRPRR 922
            . .:.|:.:....:||...|.                                       :.|.:
 Frog   892 G-ETESVKTMIVHDDVESEPA---------------------------------------MTPSK 916

  Fly   923 EKTESVIVLQNAAVRAQRLQQLQQQQQQQQLQQQQQQQNRGGGGGGGGGGGGGGSSGVGADGTGL 987
            |.|   ::::.:.|..:|..||:                           ..|.:|.:
 Frog   917 EGT---LIVRQSTVDKKRANQLE---------------------------SNGFASRI------- 944

  Fly   988 GTPGTRTSSVLPDLLSQASPATPPRHDKSSSEEYQAAISSSVHSTPSKSFIASSGSGGLGLGGGT 1052
                    .:|||||.|:       |..|::       ||...|.|:.:.
 Frog   945 --------HLLPDLLQQS-------HSSSTT-------SSPTSSQPTPTM--------------- 972

  Fly  1053 VVGGVIISSNHSPQSTISLASSSSNSRQNSPKNSISKTRSSSSITNLLHKSASSSSANLHHLTPC 1117
                    |..:||..:     ::|..| |..|::.|.:||||.|..:       ...|..::|.
 Frog   973 --------SPQTPQDKL-----TANETQ-SASNTLQKHKSSSSFTPFI-------DPRLLQISPS 1016

  Fly  1118 SSTSSASISNPLPPHAYALQQKQRSFLTFGFG-------AGGSGPSRRESHVNVNVTPTSHEAAN 1175
            |.|:..|:...:  .......|..:|:..||.       |....|:|:.|.||||  ||:....:
 Frog  1017 SGTTVTSVGTYM--RTLEANLKNTNFILVGFSSEALRPDAMRQDPTRKGSVVNVN--PTNTRPQS 1077

  Fly  1176 DTPEIRKYKKRFNSEILCAALWGVNLLIGTENGLMLLDRSGQGKVYQLISRRRFQQMEVLEGQNI 1240
            |||||||||||||||||||||||||||:|||:||||||||||||||.||:|||||||:||||.|:
 Frog  1078 DTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNV 1142

  Fly  1241 LVTISGKKNRVRVYYLSWLKSKILRTDGLSDQVERRNGWINVGDLQGAVHFKIVKYERIKFLVIA 1305
            |||||||||::||||||||::|||..|   .:||::.||..||||:|.||:|:||||||||||||
 Frog  1143 LVTISGKKNKLRVYYLSWLRNKILHND---PEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIA 1204

  Fly  1306 LKDSIEIYAWAPKPYHKFMAFKNFGELEHRPLLVDLTIEDQSRLKVIYGSAEGFHAVDLDSAEVY 1370
            ||.|:|:|||||||||||||||:||:|.|||||||||:|:..||||||||..||||||:||..||
 Frog  1205 LKSSVEVYAWAPKPYHKFMAFKSFGDLVHRPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGAVY 1269

  Fly  1371 DIYLPKHTQGAIIPHCIVALPNSNGMQLLLCYDNEGVYVNTVGRVSKNIVLQWGEMPTSVAYIGT 1435
            |||||.|.|.:|.||.|:.|||::||:||:||::|||||||.||::|::||||||||||||||.:
 Frog  1270 DIYLPTHIQSSIQPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRS 1334

  Fly  1436 GQIMGWGNKAIEIRSVESGHLDGVFMHKKAQRLKFLCERNDKVFFSSAKGASSCQIYFMTLNKPG 1500
            .||||||.|||||||||:||||||||||:||||||||||||||||:|.:...|.|:|||||.:..
 Frog  1335 NQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRSS 1399

  Fly  1501 MANW 1504
            :.:|
 Frog  1400 LLSW 1403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	234/270 (87%)
		S_TKc	32..296	CDD:214567	228/263 (87%)
		CNH	1183..1484	CDD:214481	232/300 (77%)
map4k4	XP_002934552.1	STKc_MAP4K4_6_N	8..289	CDD:270806	240/279 (86%)
		CNH	1085..1383	CDD:214481	232/300 (77%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	480	1.000	Domainoid score	I416
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1126	1.000	Inparanoid score	I227
OMA	1	1.010	-	-		QHG46069
OrthoDB	1	1.010	-	-		D246443at33208
OrthoFinder	1	1.000	-	-		FOG0001422
OrthoInspector	1	1.000	-	-		otm48244
Panther	1	1.100	-	-	O	PTHR48015
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X885
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080