Protein Alignment Ref1 and POLDIP3

DIOPT Version :9

• Sequence 1: NP_651968.1
• Gene: Ref1 / 44029
• FlyBaseID: FBgn0010774
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: NP_001265586.1
• Gene: POLDIP3 / 84271
• HGNCID: 23782
• Length: 438
• Species: Homo sapiens
• Alignment Length: 145
• Identity: 41/145 - (28%)
• Similarity: 59/145 - (40%)
• Gaps: 46/145 - (31%)

  Fly   109 TRLIVGNLDYGVSNTDIKELFNDFGPIKKAAVHYDRSGRSLGTADVIFERRADALKAIKQYHGVP 173
            |::.|.||...|:..||.|||...|.:|:|.:.:.      |.|:|:|.::.||:.|.|:|:...
Human   297 TKMTVNNLHPRVTEEDIVELFCVCGALKRARLVHP------GVAEVVFVKKDDAITAYKKYNNRC 355

  Fly   174 LDGRPMTIQL------AVSDVAVLTRPVAATDVK------RRVGG-------------------- 206
            |||:||...|      ..||..:|.|...:..:|      |||..
Human   356 LDGQPMKCNLHMNGNVITSDQPILLRLSDSPSMKKESELPRRVNSASSSNPPAEVDPDTILKALF 420

  Fly   207 --------TAPTSFK 213
                    |.||.||
Human   421 KSSGASVTTQPTEFK 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ref1	NP_651968.1	RRM	<108..>187	CDD:223796	28/83 (34%)
		RRM_THOC4	109..183	CDD:241124	27/73 (37%)
		FoP_duplication	214..>265	CDD:290576	41/145 (28%)
POLDIP3	NP_001265586.1	RRM_SKAR	297..365	CDD:241125	27/73 (37%)
		RRM	<301..424	CDD:223796	35/128 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0533
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19965
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910