Protein Alignment Ref1 and Myef2

DIOPT Version :10

• Sequence 1: NP_651968.1
• Gene: Ref1 / 44029
• FlyBaseID: FBgn0010774
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: NP_001013223.2
• Gene: Myef2 / 679712
• RGDID: 1306547
• Length: 591
• Species: Rattus norvegicus
• Alignment Length: 221
• Identity: 54/221 - (24%)
• Similarity: 95/221 - (42%)
• Gaps: 44/221 - (19%)

  Fly    49 GANAGGSPRKPGSVLKGPRGG-VAAGAVQKAKFPRGDVNSA-WKHDMYDGPKRGAVGGGSGPTRL 111
            |.||..:.::.|:..:|.... |.:|.|   ..|...||:. ...::.:..:.|.:|     :.:
  Rat   170 GENARRALQRTGTSFQGSHASDVGSGLV---NLPPSIVNNPNIPPEVINNLQAGRLG-----STI 226

  Fly   112 IVGNLDYGVSNTDIKELFNDFGPIKKAAVHYDRSGRSLGTADVIFERRADALKAIKQYHGVPLDG 176
            .|.|||:.|....:||:|:..|.:|:|.:..|:.|:|.|...|.||:..:|::||..::|..|..
  Rat   227 FVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFD 291

  Fly   177 RPMTIQLAVSDV------------AVLTR--------------PVAAT--DVKRRVGGTAPTSFK 213
            |||.:::....|            :.|.|              |::|:  ::...:|...|:...
  Rat   292 RPMHVKMDDKSVPHEDYRSHDSKTSQLPRGLGGIGMGLGPGGQPISASQLNITGVMGNLGPSGMG 356

  Fly   214 RGGGQAGGTARRGFKRPVGGKPAAGG 239
            ..|...||..|      :||....||
  Rat   357 MDGPGFGGVNR------IGGGVGFGG 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ref1	NP_651968.1	sex-lethal	31..>184	CDD:273740	39/136 (29%)
		RRM_THOC4	109..183	CDD:410081	26/73 (36%)
		FoP_duplication	202..>260	CDD:464005	10/38 (26%)
Myef2	NP_001013223.2	RRM1_MYEF2	92..167	CDD:410059
		PABP-1234	115..>587	CDD:130689	54/221 (24%)
		RRM2_MYEF2	224..299	CDD:410061	26/74 (35%)
		RRM3_MYEF2	515..591	CDD:410063