Protein Alignment Ref1 and alyref

DIOPT Version :10

• Sequence 1: NP_651968.1
• Gene: Ref1 / 44029
• FlyBaseID: FBgn0010774
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: NP_001098578.1
• Gene: alyref / 560127
• ZFINID: ZDB-GENE-070928-29
• Length: 280
• Species: Danio rerio
• Alignment Length: 288
• Identity: 129/288 - (44%)
• Similarity: 167/288 - (57%)
• Gaps: 43/288 - (14%)

  Fly     1 MVDKIEMSLDDIIKSTRSQKKPQAARGGPGGARKTGGQQRFAGGARRGGANAGGSPRKPGSVLKG 65
            |.||::||||||||..| |:.....|||.||   .||:....||.|.||..|.|.....|....|
Zfish     1 MADKMDMSLDDIIKQNR-QRGGGGGRGGRGG---RGGRGATTGGGRGGGGGASGRLGNTGGGFGG 61

  Fly    66 PRGG---------VAAGAVQKAKFPR-GDVNSAWKHDMYD-------GPKRGAVGGGSGPT---R 110
            ..||         ::.|..:.|.:.| ..:...|:||::|       |...|..|||:|..   :
Zfish    62 RGGGSGPMRNRQNLSRGRSRPAPYSRPKQLPDKWQHDLFDNGYSSNAGGGGGGGGGGAGVETGGK 126

  Fly   111 LIVGNLDYGVSNTDIKELFNDFGPIKKAAVHYDRSGRSLGTADVIFERRADALKAIKQYHGVPLD 175
            |:|.|||:|||:.||:|||.:||.:|||||||||||||||||||.|||:||||||:|||:|||||
Zfish   127 LLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLD 191

  Fly   176 GRPMTIQLAVSDVAVLTR-PVAATD------VKRRVGGTAPTSFKRG-GGQAGGTARRGFKRPVG 232
            ||||.|||..|.:....| |:...:      .:.||||   ...::| ||:.||:..||    .|
Zfish   192 GRPMNIQLVTSQIDAQRRTPMQGLNRGGGGMNRNRVGG---FGMQKGRGGRGGGSRGRG----RG 249

  Fly   233 GKPAAGGQRRERKAPPTAEELDAELDSY 260
            |:...||.:::.    :||||||:||:|
Zfish   250 GRGGGGGSKQQL----SAEELDAQLDAY 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ref1	NP_651968.1	sex-lethal	31..>184	CDD:273740	84/172 (49%)
		RRM_THOC4	109..183	CDD:410081	56/76 (74%)
		FoP_duplication	202..>260	CDD:464005	23/58 (40%)
alyref	NP_001098578.1	RRM_THOC4	126..199	CDD:410081	56/72 (78%)