DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ref1 and hnrnpa1

DIOPT Version :10

Sequence 1:NP_651968.1 Gene:Ref1 / 44029 FlyBaseID:FBgn0010774 Length:266 Species:Drosophila melanogaster
Sequence 2:XP_012812298.1 Gene:hnrnpa1 / 496507 XenbaseID:XB-GENE-493963 Length:362 Species:Xenopus tropicalis


Alignment Length:223 Identity:55/223 - (24%)
Similarity:79/223 - (35%) Gaps:49/223 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 RKPGSVLKGPRGGVAAGAVQKAKFPRGDVNSAWKHDMYDG----PKRGA-------VGGGSGPTR 110
            |.|.|  |..||   .|.|..:.....|...:.:....||    |||..       .|......:
 Frog    47 RDPNS--KRSRG---FGFVTYSSTDEVDAAMSARPHKVDGRVVEPKRAVSREDSSRPGAHLTVKK 106

  Fly   111 LIVGNLDYGVSNTDIKELFNDFGPIKKAAVHYDR-SGRSLGTADVIFERRADALK-AIKQYHGVP 173
            :.||.:........::|.|..:|.|:...:..|| ||:..|.|.|.||......| .|::||.|.
 Frog   107 IFVGGIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFEDHDSVDKIVIQKYHTVN 171

  Fly   174 LDGRPMTIQLAVSDVAVLTRPVAATDVKRRVGGTAPTSFK------------------RGGGQA- 219
            .....:...|:..::|      :.:..:|..||:...|.:                  ||||.. 
 Frog   172 NHNCEVRKALSKQEMA------SVSGSQRGRGGSGNFSGRGGFGNDNFGGRGGNFSSNRGGGFGN 230

  Fly   220 ---GGTARRGFKRP--VGGKPA-AGGQR 241
               ||....||...  .||.|. :||.|
 Frog   231 RGYGGDGYNGFGNDGGYGGSPPYSGGNR 258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ref1NP_651968.1 sex-lethal 31..>184 CDD:273740 35/139 (25%)
RRM_THOC4 109..183 CDD:410081 20/75 (27%)
FoP_duplication 202..>260 CDD:464005 18/65 (28%)
hnrnpa1XP_012812298.1 RRM1_hnRNPA1 12..92 CDD:410154 14/49 (29%)
RRM_SF 105..184 CDD:473069 21/78 (27%)
HnRNPA1 <315..>334 CDD:463312
Blue background indicates that the domain is not in the aligned region.

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