Protein Alignment Ref1 and sqd

DIOPT Version :10

• Sequence 1: NP_651968.1
• Gene: Ref1 / 44029
• FlyBaseID: FBgn0010774
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: NP_731825.1
• Gene: sqd / 41666
• FlyBaseID: FBgn0263396
• Length: 344
• Species: Drosophila melanogaster
• Alignment Length: 281
• Identity: 66/281 - (23%)
• Similarity: 101/281 - (35%)
• Gaps: 81/281 - (28%)

  Fly     6 EMSLDDIIKSTRSQKKPQAARGGPGGARKTGG---QQRFAGGARR-------GGANAGGSPR--- 57
            |::.:|..|...:. .|.:..|..|.|..|.|   .|..|.|.|.       ||.:...:.:
  Fly    10 EINGEDFTKDVTAD-GPGSENGDAGAAGSTNGSSDNQSAASGQRDDDRKLFVGGLSWETTEKELR 73

  Fly    58 ----KPG-----SVLKGPRGGVAAG----------AVQKAKFPRGDVNSAWKHDMYDGPKRGAVG 103
                |.|     :|...|:.|.:.|          |:.|.......:.::.|.|    ||:....
  Fly    74 DHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDKVSAADEHIINSKKVD----PKKAKAR 134

  Fly   104 GGSGPTRLIVGNLDYGVSNTDIKELFNDFGPIKKAAVHYDR-SGRSLGTADVIFERR---ADALK 164
            .|    ::.||.|...:|:.:||..|..||.|.:..:.:|: ..:..|...:.|:..   .|.||
  Fly   135 HG----KIFVGGLTTEISDEEIKTYFGQFGNIVEVEMPFDKQKSQRKGFCFITFDSEQVVTDLLK 195

  Fly   165 AIKQYHGVPLDGRPMTIQLAVSDVAVLTRPVAATDVKR--------RVGGT--APTSFKRGG-GQ 218
            ..||             ::|..:|          ||||        .:||.  .|....||| |.
  Fly   196 TPKQ-------------KIAGKEV----------DVKRATPKPENQMMGGMRGGPRGGMRGGRGG 237

  Fly   219 AGGTARRGFKRPVGGKPAAGG 239
            .||  |.|:.....|:.:.||
  Fly   238 YGG--RGGYNNQWDGQGSYGG 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ref1	NP_651968.1	sex-lethal	31..>184	CDD:273740	40/188 (21%)
		RRM_THOC4	109..183	CDD:410081	18/77 (23%)
		FoP_duplication	202..>260	CDD:464005	15/49 (31%)
sqd	NP_731825.1	RRM1_hnRNPA_hnRNPD_like	58..129	CDD:409763	12/74 (16%)
		RRM2_hnRNPD_like	137..211	CDD:240775	23/96 (24%)