Protein Alignment Ref1 and aly-3

DIOPT Version :9

• Sequence 1: NP_651968.1
• Gene: Ref1 / 44029
• FlyBaseID: FBgn0010774
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: NP_001076697.1
• Gene: aly-3 / 178157
• WormBaseID: WBGene00000122
• Length: 240
• Species: Caenorhabditis elegans
• Alignment Length: 279
• Identity: 82/279 - (29%)
• Similarity: 122/279 - (43%)
• Gaps: 72/279 - (25%)

  Fly     5 IEMSLDDIIKSTRSQKKPQAARGGPGGARKTGG--QQRFAGGARRGGANAGGSPRKPGSVLKGPR 67
            :::||:|||..|                |||.|  |::..||||||.....|.||:.|.     .
 Worm     7 VDLSLEDIISKT----------------RKTTGSIQKKSFGGARRGNTRPTGLPRRSGG-----S 50

  Fly    68 GGVAAGAVQKAKFPRGDVNSAWKH-DMYDGPKRGAVGGGSGPTRLIVGNLDYGVSNTDIKELFND 131
            ||                   ||. |........:.|..|...|:.:.||...|.::|::|||.|
 Worm    51 GG-------------------WKDLDAVQNHGISSRGNDSKVIRVNISNLAPTVISSDLEELFGD 96

  Fly   132 FGPIKKAAVHYDRSGRSLGTADVIFERRADALKAIKQYHGVPLDGRPMTIQLAVSDVAVLTRPVA 196
            : .:...:|:::..|.||||.|:...:| ||.:.::::.||.|||:.|  :.||.|.:.:...|.
 Worm    97 Y-RLSSVSVNFNEHGDSLGTGDISLTKR-DAERLVQKFSGVALDGKIM--KFAVIDSSNMAGRVD 157

  Fly   197 ATDVKRRVGGTA--------------PTSFKRGGGQA-----GGTARRGFKRPVGGKPAAGGQRR 242
            ..:..|...|.:              |..|.|.|..|     ||..|.||::  ||:    |..|
 Worm   158 FGNRSRSSPGRSSRGFQSGPRRNNGKPEDFLRDGVHAGDIKRGGAGRGGFRK--GGR----GGAR 216

  Fly   243 ERKAPPTAEELDAELDSYI 261
            :.|...|..||||||::|:
 Worm   217 DAKPKKTEAELDAELEAYM 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ref1	NP_651968.1	RRM	<108..>187	CDD:223796	27/78 (35%)
		RRM_THOC4	109..183	CDD:241124	25/73 (34%)
		FoP_duplication	214..>265	CDD:290576	21/53 (40%)
aly-3	NP_001076697.1	RRM_Aly_REF_like	74..146	CDD:240864	25/75 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165198
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	81	1.000	Inparanoid score	I3780
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58344
OrthoDB	1	1.010	-	-		D1369069at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14420
orthoMCL	1	0.900	-	-		OOG6_101458
Panther	1	1.100	-	-	LDO	PTHR19965
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5291
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.940