Protein Alignment Ref1 and Ref1

DIOPT Version :10

• Sequence 1: NP_651968.1
• Gene: Ref1 / 44029
• FlyBaseID: FBgn0010774
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: XP_309011.4
• Gene: Ref1 / 1270326
• VectorBaseID: AGAMI1_001459
• Length: 271
• Species: Anopheles gambiae
• Alignment Length: 301
• Identity: 146/301 - (48%)
• Similarity: 184/301 - (61%)
• Gaps: 66/301 - (21%)

  Fly     1 MVDKIEMSLDDIIKST----------------RSQKKPQAARGGPGGARKTGGQQRF-AGGARRG 48
            ||||||||||:||||.                ||.::|.|   |.|||...|.:..| :||.|.|
Mosquito     1 MVDKIEMSLDEIIKSQKSTRPRGGGGRAGGAGRSNRRPGA---GSGGASGGGARNGFRSGGQRNG 62

  Fly    49 GANAGGSPRKPGSVLKG-PRGGVAAGAVQKAKFPRGDVNSAWKHDMYDGPKRG---------AVG 103
            ||:.|      |.|||| .|||:.     :|::.|||||||||||||:||::.         ..|
Mosquito    63 GASGG------GGVLKGRTRGGIT-----RARYGRGDVNSAWKHDMYEGPRKNRLLAAAGGLGAG 116

  Fly   104 GGSGPTRLIVGNLDYGVSNTDIKELFNDFGPIKKAAVHYDRSGRSLGTADVIFERRADALKAIKQ 168
            |..|..:|:|.|||:|||.|||.|||.:|||::.|:|||||||||||||||:||||:||:||:||
Mosquito   117 GPGGAAKLLVSNLDFGVSETDINELFAEFGPLRSASVHYDRSGRSLGTADVVFERRSDAIKAMKQ 181

  Fly   169 YHGVPLDGRPMTIQLAVSDV--------AVLTRPVAATDVKRRVGGTAPTSFKRG-GGQAGGTAR 224
            |:|||||||||:||:|.|::        |||....:|...::..||       || ||::.|.
Mosquito   182 YNGVPLDGRPMSIQMATSEIPAPRVPRPAVLAASASARSPRKPAGG-------RGAGGKSQGR-- 237

  Fly   225 RGFKRPVGGKPAAGGQRRERKAPPTAEELDAELDSYINDMK 265
                   ||:...||.||:.:...||||||||||:|..|||
Mosquito   238 -------GGRGGGGGGRRQPRETKTAEELDAELDAYTKDMK 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ref1	NP_651968.1	sex-lethal	31..>184	CDD:273740	93/163 (57%)
		RRM_THOC4	109..183	CDD:410081	54/73 (74%)
		FoP_duplication	202..>260	CDD:464005	23/58 (40%)
Ref1	XP_309011.4	None