Protein Alignment Ref1 and ALYREF

DIOPT Version :9

• Sequence 1: NP_651968.1
• Gene: Ref1 / 44029
• FlyBaseID: FBgn0010774
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: NP_005773.3
• Gene: ALYREF / 10189
• HGNCID: 19071
• Length: 264
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 136/274 - (49%)
• Similarity: 163/274 - (59%)
• Gaps: 38/274 - (13%)

  Fly     1 MVDKIEMSLDDIIKSTRSQKKPQAARGGPGGARKTG--GQQRFAGGARRGGA------NAGGSP- 56
            |.||::||||||||..|||      |||.||.|..|  |.|    |.|.|||      |.||.|
Human     8 MADKMDMSLDDIIKLNRSQ------RGGRGGGRGRGRAGSQ----GGRGGGAQAAARVNRGGGPI 62

  Fly    57 RKPGSVLKGPRGGVAAGAVQKAKFPR-GDVNSAWKHDMYDGPKRGAVGGGSGPT---RLIVGNLD 117
            |...::.:|..||  .|..:.|.:.| ..:...|:||::|    ...|||:|..   :|:|.|||
Human    63 RNRPAIARGAAGG--GGRNRPAPYSRPKQLPDKWQHDLFD----SGFGGGAGVETGGKLLVSNLD 121

  Fly   118 YGVSNTDIKELFNDFGPIKKAAVHYDRSGRSLGTADVIFERRADALKAIKQYHGVPLDGRPMTIQ 182
            :|||:.||:|||.:||.:|||||||||||||||||||.|||:||||||:|||:|||||||||.||
Human   122 FGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQ 186

  Fly   183 LAVSDVAVLTRPVAATDVKRRVGGTAPTSFKRGGGQAGGTARRGFKRPVGGKPAAG-GQRRERKA 246
            |..|.:....||  |..|.|  ||........|.|..||| |||.:   ||....| |..|..|.
Human   187 LVTSQIDAQRRP--AQSVNR--GGMTRNRGAGGFGGGGGT-RRGTR---GGARGRGRGAGRNSKQ 243

  Fly   247 PPTAEELDAELDSY 260
            ..:||||||:||:|
Human   244 QLSAEELDAQLDAY 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ref1	NP_651968.1	RRM	<108..>187	CDD:223796	58/81 (72%)
		RRM_THOC4	109..183	CDD:241124	56/76 (74%)
		FoP_duplication	214..>265	CDD:290576	23/48 (48%)
ALYREF	NP_005773.3	FYTT	4..>23	CDD:284488	11/14 (79%)
		RRM	<114..>210	CDD:223796	66/99 (67%)
		RRM_THOC4	114..187	CDD:241124	56/72 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I5976
eggNOG	1	0.900	-	-		E1_KOG0533
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3772
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58344
OrthoDB	1	1.010	-	-		D1369069at2759
OrthoFinder	1	1.000	-	-		FOG0001223
OrthoInspector	1	1.000	-	-		oto88962
orthoMCL	1	0.900	-	-		OOG6_101458
Panther	1	1.100	-	-	LDO	PTHR19965
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5291
SonicParanoid	1	1.000	-	-		X843
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.870