Protein Alignment Ref1 and Alyreffm10

DIOPT Version :10

• Sequence 1: NP_651968.1
• Gene: Ref1 / 44029
• FlyBaseID: FBgn0010774
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: NP_001171006.1
• Gene: Alyreffm10 / 100043292
• MGIID: 3782524
• Length: 268
• Species: Mus musculus
• Alignment Length: 300
• Identity: 106/300 - (35%)
• Similarity: 141/300 - (47%)
• Gaps: 82/300 - (27%)

  Fly     1 MVDKIEMSLDDIIKSTRSQKKPQAARGGPGGARKTG-GQQRFAGGARRGGANAGGSPRKPGSVLK 64
            |.||::|||:||||.|:.|   |.....|......| |.:|:......||.|.
Mouse     4 MADKMDMSLEDIIKLTKIQ---QRRHDRPDSRVNRGTGSKRYRPAFTHGGRNR------------ 53

  Fly    65 GPRGGVAAGAVQKAKFPRGDVNSAWKHDMYDGPKRGA----VGGGSGPTRLIVGNLDYGVSNTDI 125
                  .|...:..:.|     ..|:||::.|..||.    .||     :|.:.||.:|||:.||
Mouse    54 ------LAPYCRPKQLP-----DKWQHDLFIGGFRGQNHVDTGG-----KLFLSNLHFGVSDADI 102

  Fly   126 KELFNDFGPIKKAAVHYDRSGRSLGTADVIFERRADALKAIKQYHGVPLDGRPMTIQLAVSDVAV 190
            :.||.:||.:||:||||||.|||||||.|.|||:||||||:::|:|.|||||||.||||.|.:..
Mouse   103 QLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDR 167

  Fly   191 LTRPVAATDVKRRVGGTAPTSFKRGGG--QAGGTARRGFKRPVGGKPAAG--------------- 238
            ..||..:   |.|.|.|.    ..|.|  ..|||.    |..:||....|
Mouse   168 QGRPAQS---KNRGGMTR----NPGSGVLSGGGTK----KWTLGGSQGRGRGTIRNSKLQQQQQQ 221

  Fly   239 ------------------GQRRERKAPPTAEELDAELDSY 260
                              .|:::::...:||||||:||:|
Mouse   222 QKQKQQQQQQKQQQKQQQKQQQKQQQQLSAEELDAQLDAY 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ref1	NP_651968.1	sex-lethal	31..>184	CDD:273740	64/157 (41%)
		RRM_THOC4	109..183	CDD:410081	47/73 (64%)
		FoP_duplication	202..>260	CDD:464005	21/92 (23%)
Alyreffm10	NP_001171006.1	hnRNP-R-Q	<26..>179	CDD:273732	72/183 (39%)
		RRM_THOC4	86..160	CDD:410081	48/78 (62%)