Protein Alignment Ref1 and Alyreffm6

DIOPT Version :10

• Sequence 1: NP_651968.1
• Gene: Ref1 / 44029
• FlyBaseID: FBgn0010774
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: NP_001160110.1
• Gene: Alyreffm6 / 100043231
• MGIID: 3782483
• Length: 289
• Species: Mus musculus
• Alignment Length: 317
• Identity: 106/317 - (33%)
• Similarity: 140/317 - (44%)
• Gaps: 88/317 - (27%)

  Fly     1 MVDKIEMSLDDIIKSTRSQKKPQAARGGPGGARKTG-GQQRFAGGARRGGANAGGSPRKPGSVLK 64
            |.||::|||:||||..:.|   |..|..|....|.| |.:|:......||.|.
Mouse     4 MADKMDMSLEDIIKLNKMQ---QGRRDRPDSRVKRGTGPKRYRPAFTHGGRNR------------ 53

  Fly    65 GPRGGVAAGAVQKAKFPRGDVNSAWKHDMYDGPKRGA----VGGGSGPTRLIVGNLDYGVSNTDI 125
                  .|...:..:.|     ..|:||::.|..||.    .||     :|.:.||.:|||:.||
Mouse    54 ------LAPYCRPKQLP-----DKWQHDLFIGGFRGQNHVDTGG-----KLFLSNLHFGVSDADI 102

  Fly   126 KELFNDFGPIKKAAVHYDRSGRSLGTADVIFERRADALKAIKQYHGVPLDGRPMTIQLAVSDVAV 190
            :.||.:||.:||:||||||.|||||||.|.|||:||||||:::|:|.|||||||.|.|..|.:..
Mouse   103 QLLFAEFGTLKKSAVHYDRCGRSLGTAHVHFERKADALKAMREYNGAPLDGRPMNIHLVTSQIDR 167

  Fly   191 LTRPVAATD---VKRRVG-----GTAPTSFKRGGGQAGGTARRGFKR------------------ 229
            ..||...:|   :.|..|     |.....:..||.|..|   ||..|
Mouse   168 QGRPALNSDKGGMTRNPGSGVLSGGGTKRWTLGGSQGSG---RGTSRNSKLQQQQQQQQQQEEQK 229

  Fly   230 --------------PVGGKPAAGGQRRERKAPP--------TAEELDAELDSYINDM 264
                          ..|.......|::|::...        :.|||||:|| |..||
Mouse   230 HQKQQQQKQQQQQQKQGQNHQHQQQQKEQQQQQQQKELQQLSVEELDAQLD-YYQDM 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ref1	NP_651968.1	sex-lethal	31..>184	CDD:273740	64/157 (41%)
		RRM_THOC4	109..183	CDD:410081	47/73 (64%)
		FoP_duplication	202..>260	CDD:464005	20/102 (20%)
Alyreffm6	NP_001160110.1	FYTT	6..>66	CDD:462082	22/85 (26%)
		RRM_THOC4	86..160	CDD:410081	48/78 (62%)