Protein Alignment Ref1 and Gm4302

DIOPT Version :9

• Sequence 1: NP_651968.1
• Gene: Ref1 / 44029
• FlyBaseID: FBgn0010774
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: NP_001160106.1
• Gene: Gm4302 / 100043227
• MGIID: 3782482
• Length: 294
• Species: Mus musculus
• Alignment Length: 322
• Identity: 106/322 - (32%)
• Similarity: 140/322 - (43%)
• Gaps: 93/322 - (28%)

  Fly     1 MVDKIEMSLDDIIKSTRSQKKPQAARGGPGGARKTG-GQQRFAGGARRGGANAGGSPRKPGSVLK 64
            |.||::|||:||||..:.|   |..|..|....|.| |.:|:......||.|.
Mouse     4 MADKMDMSLEDIIKLNKMQ---QGRRDRPDSRVKRGTGPKRYRPAFTHGGRNR------------ 53

  Fly    65 GPRGGVAAGAVQKAKFPRGDVNSAWKHDMYDGPKRGA----VGGGSGPTRLIVGNLDYGVSNTDI 125
                  .|...:..:.|     ..|:||::.|..||.    .||     :|.:.||.:|||:.||
Mouse    54 ------LAPYCRPKQLP-----DKWQHDLFIGGFRGQNHVDTGG-----KLFLSNLHFGVSDADI 102

  Fly   126 KELFNDFGPIKKAAVHYDRSGRSLGTADVIFERRADALKAIKQYHGVPLDGRPMTIQLAVSDVAV 190
            :.||.:||.:||:||||||.|||||||.|.|||:||||||:::|:|.|||||||.|.|..|.:..
Mouse   103 QLLFAEFGTLKKSAVHYDRCGRSLGTAHVHFERKADALKAMREYNGAPLDGRPMNIHLVTSQIDR 167

  Fly   191 LTRPVAATD---VKRRVG-----GTAPTSFKRGGGQAGGTARRGFKR------------------ 229
            ..||...:|   :.|..|     |.....:..||.|..|   ||..|
Mouse   168 QGRPALNSDKGGMTRNPGSGVLSGGGTKRWTLGGSQGSG---RGTSRNSKLQQQQQQQQQQQQQQ 229

  Fly   230 -------------------PVGGKPAAGGQRRERKAPP--------TAEELDAELDSYINDM 264
                               ..|.......|::|::...        :.|||||:|| |..||
Mouse   230 QEEQKHQKQQQQKQQQQQQKQGQNHQHQQQQKEQQQQQQQKELQQLSVEELDAQLD-YYQDM 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ref1	NP_651968.1	RRM	<108..>187	CDD:223796	48/78 (62%)
		RRM_THOC4	109..183	CDD:241124	47/73 (64%)
		FoP_duplication	214..>265	CDD:290576	20/96 (21%)
Gm4302	NP_001160106.1	FYTT	6..>59	CDD:284488	21/73 (29%)
		RRM	<79..>163	CDD:223796	50/88 (57%)
		RRM_THOC4	86..160	CDD:241124	48/78 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I5923
eggNOG	1	0.900	-	-		E1_KOG0533
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	202	1.000	Inparanoid score	I3746
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1369069at2759
OrthoFinder	1	1.000	-	-		FOG0001223
OrthoInspector	1	1.000	-	-		otm42753
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19965
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X843
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.930