Protein Alignment sbb and znf609a

DIOPT Version :10

• Sequence 1: NP_001261074.1
• Gene: sbb / 44027
• FlyBaseID: FBgn0285917
• Length: 2330
• Species: Drosophila melanogaster
• Sequence 2: XP_005174270.1
• Gene: znf609a / 793767
• ZFINID: ZDB-GENE-030131-6219
• Length: 1399
• Species: Danio rerio
• Alignment Length: 1793
• Identity: 405/1793 - (22%)
• Similarity: 610/1793 - (34%)
• Gaps: 620/1793 - (34%)

  Fly   685 GTGQSGGSSSMSAVPPGV--FTPSAGSPSTGSPSTVVPAAASLLAATGAASSSASQMASSSAGGV 747
            |.|.:..||:::|:|..:  ..|....|...|.|   .|..|..:.....||:...:...:.|..
Zfish    55 GDGMAAASSAVAALPDNIKFINPVPPPPIKDSKS---KAKRSKNSKDSTKSSTPDGVKKDAQGRT 116

  Fly   748 GGSGGGANAPG-PPGKESAGSIKISSHIAA---QLAAAAASNSYSGSGANTNQ------------ 796
            ...|.|..|.. |.||.|..:.|.|.::.:   ...|:..|......|..|..
Zfish   117 QNEGAGPTAGNLPSGKGSDKANKASRNVQSGKKDKEASGKSKKEKNEGVQTGNVPSEKDSLVQVI 181

  Fly   797 --GQNSNAGGNGGSESKAAAAAQ---AKLMAPGMI------------------------SATMHH 832
              ||..|........|....|.|   ..|...|:|                        |..|..
Zfish   182 PLGQARNTPFEATQNSDLVGADQLGNITLDTTGIITPLAIKSEPEEVENNDCRSMKKVKSEKMES 246

  Fly   833 TISVPAGTGTGDDDTKSPPAKRVKHEAGASGAGGGKEMV-----DICIGTS-VGTITEPDCLGPC 891
            .:|.||           ||...:....|.|......|.:     .:.:.|| |...|||:|||||
Zfish   247 PVSTPA-----------PPPLHLLAPVGNSEISSSCEQIMVRTRSVAVNTSDVALATEPECLGPC 300

  Fly   892 EPGTSVTLEGIVWHETEGGVLVVNVTWRGKTYVGTLLDCTRHDWAPPRFCDSPTEELDSRTPKGR 956
            ||||||.||||||.|||.|:||||||||.|||||||||||||||||||||:|||.:|:.|..:||
Zfish   301 EPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCESPTSDLEMRNGRGR 365

  Fly   957 GKRGRSAGLTP--DLSNFTETRSSIYFSHAQVHSKLRNGA-TKG-RGATRSASGNAAANSNSSSS 1017
            |||.|....||  :.||.::.:.|       .:||.|..: :|| ||:..|:......|||:...
Zfish   366 GKRMRPNSNTPVNENSNSSDNKGS-------NNSKTRAASNSKGRRGSQNSSERRTPPNSNTEDV 423

  Fly  1018 GNGGGATPSTSPTAFLPPRPEKRKSKDEAPSPLNGDASDGASVGGIGGAGGVNMVNASGIPISAS 1082
                .|:||::         .|||:|..:....|..:.|      ..|:..:...:.||||.:.
Zfish   424 ----KASPSSA---------NKRKNKPPSDMEPNSSSED------TKGSKRMRTNSNSGIPHTV- 468

  Fly  1083 GGGLATQPQSLLNPVTGLNVQISTKKCKTASP-----CAISPVLLECPEQDCSKKYKHANGLRYH 1142
                               :.:|..|.::..|     |: ||||::||..:|:|||||.|||:||
Zfish   469 -------------------LPLSNVKAESLPPSLDRSCS-SPVLIDCPHPNCNKKYKHINGLKYH 513

  Fly  1143 QSHAHGAGGGASSMDEDSMQAPEDPATPPSPGVASGTGSGASVASSAVPATAPSAGQGTVAVSPN 1207
            |:.||........:|.|| :..||....|.||..:|........:|...:..|. |:|..|.||:
Zfish   514 QARAHNDDDVKLDIDGDS-ENGEDSTLHPEPGSCNGASISQKGCASPARSVTPK-GRGFDAQSPS 576

  Fly  1208 TPLANSSN---------------PVTNGNVAP------------------SAPATGSVTIAAPNT 1239
            .....||.               |:......|                  .|...||
Zfish   577 PSGKMSSKQPGKKKSDAEHDSGMPMDGCEDGPCLTDDTSNDGIDDKRGLDKAKKAGS-------- 633

  Fly  1240 TPSVVETQAPLTGPPPVTPPAPT------PICAVATP--GAEQSVSSVLPLGNLPLTAGPNSATQ 1296
             .|.:..:|..:..||:.|..||      |......|  |:..|:.||:.   .|::..|.....
Zfish   634 -GSKLAQKAMKSARPPLVPSMPTQQLYNLPASGFPAPSSGSSTSMGSVVV---QPISKSPQLKNI 694

  Fly  1297 QQQP-----PTQQQQPQLLVPGGSAASLQQQQQQQ------QPVA-GGSITAGISGQALSQHQQQ 1349
            |.:|     |...|    .|.|......:.:::::      .|.| ||....|.|..:.|..|..
Zfish   695 QPKPAVIADPAMNQ----AVSGSKDKKKKDKKKKEGGKEGDSPKAKGGKPEEGKSPYSESSDQGG 755

  Fly  1350 LMGGLPAMLSDQQQQALLQQGALKAGVLRFGPPDGNPLQQQP--GQASVNPQTQQSPPRPPSHVQ 1412
            ...|:....||..|..|....|....:..|.  |.:|   .|  |.||.......:.|..|.||.
Zfish   756 RNEGMLNGSSDPHQSRLASMKAEADKIYSFS--DNSP---SPCIGVASRIETGGIAQPLTPLHVV 815

  Fly  1413 DQQTPSAYAQQAGLKTSPGFGSVGVGAASSKQKKNRKSPGPSDFEGRVSREDVQSPAYSDISD-- 1475
            .|.                      ||.:|..|.|                   |||||||||
Zfish   816 TQN----------------------GADNSSVKTN-------------------SPAYSDISDAG 839

  Fly  1476 -------DSTPVAEQEMLDKSVGQAVTAKHIELMGKK---PTEVGVGVPPPPAPNMYVPGMYQFY 1530
                   |||.|..:   |.:|.:.         .||   |::      ||...:.|.|| :::|
Zfish   840 EDGEGKVDSTKVKSE---DPAVREG---------AKKTLFPSQ------PPNKDSSYYPG-FEYY 885

  Fly  1531 PAQQQSAPPPQQQQQQPQYMVQTEPGKPPGLPPALTQAQQQQQLQ----PGAPPPTSQPPSHLLG 1591
            .....:...|..........:|..|.|        .:.:::.:||    |.:.||..:.|..::|
Zfish   886 SPNNNTYGNPSPGVSNTATSLQEGPVK--------VKKEEEPELQGIEKPKSEPPEDRKPDVVVG 942

  Fly  1592 PPGQQSVAAHLADYSGKNKDPPLDLMTKPQPQPGQPPSQQQQSGQLSGQENNGKDVGPPTSQPGS 1656
            ...||                      :.|.|..||...||:|...                  .
Zfish   943 SSQQQ----------------------QQQQQQQQPSVIQQRSSMF------------------M 967

  Fly  1657 QPPPVNLSAVAGPPPGSLPPGLGGLSALGAAGLGGPGPGKGMPHFYPFNFIP-PAYPYNVDPNFG 1720
            ||...|..|                                  :.:||.:.| .||
Zfish   968 QPLYYNQYA----------------------------------YVHPFGYSPDQAY--------- 989

  Fly  1721 SVSIVASEEAAKLSGHPGLPPSSQAQQLSGISIKEERLKESPSPHDQPKHMPSQQQMIASKLIKQ 1785
                           |..|...:..||.      |:|.::...     :|..|:::..|::..::
Zfish   990 ---------------HNHLMNPAYRQQC------EDRQRQVAE-----QHRASEKKSEAAQKERE 1028

  Fly  1786 EPMTKQEIKQEPNSNPGQQHPPPQQQPAPQPQQQQPPPPQPQQPHALHPKDLQALGAYPAIYQRH 1850
            ..|..:|.||:.:       .||....||.......|.||.:      ||:....|.
Zfish  1029 AQMKPEEWKQKAS-------VPPTLSKAPSVSDLGKPSPQGK------PKESAEPGK-------- 1072

  Fly  1851 SINLAVQQAREEELRRYYMFTGRQNSAAAAAAAAAQNAASGGLPPHPGMMHKDE--PGMGSAAQQ 1913
              ::.:.:..|          |:..|..........:.|.     |.|   |||  |.:.|.
Zfish  1073 --SVIIPKGEE----------GKGPSQQGEGLKMKLSEAG-----HHG---KDEQKPSLESG--- 1114

  Fly  1914 QQQQQQQQMQIAQQQQQAIQQHHQHLQQQHQAQQQ---QQQQQHQQQQQQQQQQQQQQQQQQQQQ 1975
             :...:|.|.:.:|:..:....:.:..:....|:|   ::.::.:::.:::::.:.:.:::::::
Zfish  1115 -RSAMEQAMYMYRQEPDSRLWPYVYPSKYPDPQKQIDEERWKEERERDREREKDRDRDRERERER 1178

  Fly  1976 KLKQSQAASAGANNKATNLTKDSPKQKGGDDDQPLKVKQEGQKPTMETQGPPPPPTSQYFLHPSY 2040
            |.|..:.......:|..|  |:.|:.....::.  :|.::   |....|.  ..|.:|:..:.||
Zfish  1179 KSKDERQRPKDTPSKEEN--KEEPRTSSSAEEH--RVSKD---PRAHMQF--STPLAQHQSYMSY 1234

  Fly  2041 ISPTPF--GFDPNHPMYRN----VLMSAAGPYNTAPYHLPIPRPY---HAP---EDLSRNTGT-- 2091
            :...|:  |:||:||.||.    |:.:..|.|.:..|..   .||   .||   .:.:|::.|
Zfish  1235 MHGYPYGQGYDPSHPGYRGMPAVVMQNYPGSYLSPGYSF---SPYGSKMAPGEEAEKARSSPTVS 1296

  Fly  2092 -------KALDALHHAASQYYTTHKIHELSERALKSPTSGSGPVKVSVSSPSIGPPQPGGPTSSG 2149
                   ||||.|...||||.:            ||||         |:..:....:..|.....
Zfish  1297 GKSASESKALDMLQQHASQYKS------------KSPT---------VAEKTTHDRERSGAERER 1340

  Fly  2150 PGSGPVSGVLGPGSGSNQQPGSAPGSAGGVPLNLQPPPGGMGPSPGSKPDLSGPKGHGGVTPGSS 2214
            .|..|
Zfish  1341 DGERP------------------------------------------------------------ 1345

  Fly  2215 LDGHKQSMPGGPPPNGPSGNGAVGGVGGAAGNGAAGGGGAGAADSRSPPPQRHVHTHHHTHVGLG 2279
                                                         ||.|.||.:.:|||    ||
Zfish  1346 ---------------------------------------------RSSPSQRMIPSHHH----LG 1361

  Fly  2280 YPMYPAPY---------GAAVLASQQAAAVAVINPFPP 2308
            |.:.|..|         .:|::|||||:|.::   :||
Zfish  1362 YQLLPGQYDLSYATGISSSAIVASQQASAPSL---YPP 1396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sbb	NP_001261074.1	PRK10856	<1143..>1245	CDD:236776	27/134 (20%)
		PHA03247	<1162..1454	CDD:223021	72/346 (21%)
znf609a	XP_005174270.1	SFP1	<495..534	CDD:227516	19/39 (49%)