Protein Alignment GOLGA6L22 and lva

DIOPT Version :9

• Sequence 1: NP_001382774.1
• Gene: GOLGA6L22 / 440243
• HGNCID: 50289
• Length: 810
• Species: Homo sapiens
• Sequence 2: NP_001284849.1
• Gene: lva / 31350
• FlyBaseID: FBgn0029688
• Length: 2779
• Species: Drosophila melanogaster
• Alignment Length: 942
• Identity: 196/942 - (20%)
• Similarity: 422/942 - (44%)
• Gaps: 197/942 - (20%)

Human     8 SKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTSPETTTSGGCHSPEDE-------QKASH 65
            |:|.:..::|.:.:|:|...:....||:::                    |||       .:.:.
  Fly   848 SRLRQELDELRESYPETEAPLAIVGSDSQR--------------------EDEILQLQSQLEDAR 892

Human    66 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHA-----------------------VKQLE 107
            ..|...|:::|.||..|:.|...:.| |:.|...|.|                       .||||
  Fly   893 SLQAEQRQQIEEQVDQIKELRQTEAE-QLQLVARQSAEITQLQLQSEQFDQLLNSKEMSHEKQLE 956

Human   108 GEA---RDLISRLHDSWKFAGELEQALSAVTTQKKKADRYIEELTKERDALSLELYRNTITDEEL 169
            .:.   |:|.:|..   ...|||....:.|..||:   :.||.:::...||:|::.......|||
  Fly   957 QQTRIRRELEARAE---SLEGELSILQTLVAEQKQ---QLIESVSESEHALNLKMLELQSAQEEL 1015

Human   170 KEKNAK-----LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 229
            :|..||     |:|.|::   .||.:...|:||....|....|..|.|.....:|..||.|..:.
  Fly  1016 RELRAKEDPDQLREALRV---SKSLVAQQVRELTSSQETVDALNQQIQEYQGLEHAHKEEQFKNR 1077

Human   230 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE---QEEKMRRQE 291
            :|:.::::..|..:...|....:   |:|:||...::|||:|.::::||..||   ...::.:.:
  Fly  1078 ELREKLKKYALNLKKRTQDNADL---EQKVQELTSQLQEQQELVKQKEEVEREPIVDNHRVEQLQ 1139

Human   292 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK-IREQEEKRQEEEKIREQEKRQEQEA--- 352
            :.:.:..|.::.:..:..|..:.:|:|::::.|||: |:|::.:.|:...:.::.:|:.|||
  Fly  1140 QQVSKLNEDLKAKIHLNLENRDALRQLKQQIQEQEQLIQERDAELQDANLVSKELRRERQEADQE 1204

Human   353 --KMWRQEEKIREQEEKIREQ----------------------EKKMWRQEEKIHEQEKIREEEK 393
              ::.::..::||:..|::|:                      |.|. ::.||..|..|:|....
  Fly  1205 VFQLGQENSRLREEISKLQEEIHNLGQRVNEEPTAVEDLRRQLEAKS-KKFEKSKELIKLRNATI 1268

Human   394 RQEQEEMWR-QEEKIREQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKMHDQEEKIREQEEKVWR 457
            :..|.|:.: |:::..|.|.: |.....|||....:..|....|||....::.....|.::.:.:
  Fly  1269 QSLQRELQQLQQDQDSEVEHV-RNARAAHEQLRLEKDAEITALRQEILKLERSRAAGEGDDTITK 1332

Human   458 QEEKIREQEKKREQE--EKMWRQEEKIREQEEKIREQEEMWREE---------------EKMHE- 504
            ...::.|.:.:::.|  :...|:.:::|.|....:||..:..::               |.:||
  Fly  1333 TSHQLLESQSQQQAESLQVAERELQQLRVQLTAAQEQHALLAQQYASDKANFEMTIARLETLHEG 1397

Human   505 -QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 568
             |.|:        |||..:  .|.:..|..::..:...:.||...:..|:.   ..::|::..|:
  Fly  1398 IQAKL--------QEDASY--IESLEAQNTELQARSAALEEQAASQANQQA---ASQDKVQILEQ 1449

Human   569 KIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIR 633
            :::||    |||||:.|:|::.:||:..::|::|:...      ||.|.:..:.|:.|:|...:|
  Fly  1450 QLKEQ----REQEEQKRQQDQQLQERFYELGQREQAQS------RQLELLTSEAEESRQQLAGLR 1504

Human   634 EQEEKIWEQEEKI-----REQEEMMQEQEEKMGEQEEKIWEQEEKMQEQEE----KMRRQEEKIR 689
            .:.|.:..:..::     .|:|:|....:|::.|..:::..:|..:..|.:    |:..:..::.
  Fly  1505 TEYESLLAKHSQLTATAQAEREQMSSHSQEELAELRQQLDVKEADLHRQRQVYDAKLAAKATELD 1569

Human   690 EQEKKIREQEEK----IREQEEMMQEQEEKMGEQEEKMQ---EQEEKMRRQEEKIREQEKKIREQ 747
            |.|..:....|:    .||..:.::..:|.:.::.|::|   |:.:::.|:...:..:...:|.|
  Fly  1570 ELECDLNSHVERAAAETRELCQQLERSQELVAQRTEELQRLNEEFQEVERERSTLSREVTLLRLQ 1634

Human   748 ----EEKIREQEEM-MQEQEEK-----MWEQEEKMC----EQEEKMQEQ---------------- 782
                |:.:.|.:|: ||..::|     :..|.:.:|    ::.:.:|::
  Fly  1635 HDSAEQDVLELQELRMQAMQDKTEMDNLRTQIDALCANHSQELQALQQRIAELDTLGQNQTDDQV 1699

Human   783 --EEKMRRQEEKMWEQEVRL--RQQEEKMQEH 810
              |.:.:|..|::.|.:.:|  :|.:::.|:|
  Fly  1700 YIETENKRLAEQLSELQAQLARQQHQQQQQQH 1731

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GOLGA6L22	NP_001382774.1	None
lva	NP_001284849.1	SMC_prok_B	327..1151	CDD:274008	78/335 (23%)
		SMC_prok_B	952..1721	CDD:274008	171/805 (21%)
		SMC_prok_B	1475..>2183	CDD:274008	47/263 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000