Protein Alignment GOLGA6L22 and epg-2

DIOPT Version :9

• Sequence 1: NP_001382774.1
• Gene: GOLGA6L22 / 440243
• HGNCID: 50289
• Length: 810
• Species: Homo sapiens
• Sequence 2: NP_490955.1
• Gene: epg-2 / 171787
• WormBaseID: WBGene00021468
• Length: 690
• Species: Caenorhabditis elegans
• Alignment Length: 713
• Identity: 143/713 - (20%)
• Similarity: 301/713 - (42%)
• Gaps: 130/713 - (18%)

Human   173 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 237
            :|:.||.::|.|.....:...:.|.|.:         .|.|:.|...|.||  :|.||..:.:.|
 Worm    13 SAEDQEPIELAEDSLQNLDKMLAEEKEE---------HQLLKDEVVLLRKE--NVEAKTYSTLLE 66

Human   238 NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 302
            ..|     .:.|||....:|...| |..::.....:..:..:::|.:|::|:    :|..:.|
 Worm    67 IML-----DEAEEKASSAQETTSE-ENNLKILNRDLVAENLELKEMKEELRK----IWLSDSK-- 119

Human   303 RQEEMMWEKEEKIRELEEKMHEQEKIREQEE---KRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 364
            :.:|.:....::..:|::..||.|.||:..:   ....||..:.|.:.:|.|:::...|.::.|:
 Worm   120 KFQEALTRISDENTKLQKDCHELESIRQCAQFALDNCNEELEKTQTENEEHESRIETLEREVCEK 184

Human   365 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE-MWRQEE---KIREQEEIWRQKEKMHEQE- 424
            :..:    |.:..::::|..|.:::.:|......: |:.:|:   :|.:.:|.|:.|:...|.|
 Worm   185 DIAM----KDIVERKDEISLQLELQTKEFTSALNDLMYGREDTLKQIHQMKENWKVKQNEFEVEI 245

Human   425 EKIRKQEEKVWRQEEKMHDQEEKIREQEEKVWRQEEKIR-EQEKKREQEEKMWRQEEKIREQ-EE 487
            .|::.|.:....:..::.|:...:..:...|..:....| ..::|.|..|.:....:.:|:: |:
 Worm   246 TKLKSQNDYFDSERLQLTDRIRALLNELSDVRLELGSTRLAMKEKAEVTEAVTSFNKDLRDKLED 310

Human   488 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK--VWRQE-----EKIREQ 545
            :|....|..:..:..|||:           |..:...||:::...:|  .:..|     |.:||.
 Worm   311 EIARLGECLQFRKDEHEQD-----------EAVIAHLEEQLKLGSDKAAAFSSEHSDTIELLRES 364

Human   546 EEKRQE--QEEKMWKQEEKI-REQEEKIREQEEKIREQ-----EEKIREQEEMMQEQEEKM---- 598
            |.:..|  .|....|::.|| :|::|.:....|.:|||     :|:..|:.:|..|.:.||
 Worm   365 ETELMELRMENYDLKEDFKILKEEKEDVNRTCECLREQLSTTIQERDIEKGQMQSEMDAKMVAVH 429

Human   599 ---GEQEEKMQEQEKMRRQEEKIREQ------EEKIREQKEKIREQEEKIWEQEEKIREQEEMMQ 654
               .:|.:.|:....:...:|.|:.|      ::|...:...:|.:.|:.....:.:|:|..::.
 Worm   430 QQYAKQIDNMKYNHMLAINQELIKGQMALESGKKKHANEILTVRNELEQSNAAHQSLRDQCSLLL 494

Human   655 EQEEKMGE------------QEEKIWEQEEKMQEQEE-----KMRRQEEKIREQEKKIREQE--- 699
            ..|:.:..            .||.|..:..:...|:|     :..:.|..:.|..|...:|.
 Worm   495 SSEDDLRTAHLALESKMTLVSEECIALRVSRANAQKEIGNLTEHHKLEVALLEDAKSGIQQRLHY 559

Human   700 -----EKIREQEEMMQEQEEKMGEQEEKMQEQEE------KMRRQEEKIREQEKKIREQ------ 747
                 |::::..|:.|.|.:|  |.:||..|..|      .|::|...:....:.:..|
 Worm   560 ATIEIEQLKKINEVTQAQFKK--ETDEKNAEINEFQAAMVSMKQQYNVLGNHCRVLTSQGISDRT 622

Human   748 -----EEKIREQEEMMQEQEE-------KMWEQEEKMCEQ--EEKMQEQEEKMRRQEEKM-WE 795
                 :|.|||..|:..|.:.       ::.:..:|:.:.  .|::.|:.:.....|||. ||
 Worm   623 TIDKLQETIREHTELAIETKRIHDAEIVQLNDAHKKLVDNLGVEELDEEPKASTESEEKAEWE 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GOLGA6L22	NP_001382774.1	None
epg-2	NP_490955.1	SMC_prok_B	<14..413	CDD:274008	91/436 (21%)
		Smc	264..>606	CDD:224117	71/354 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000