Protein Alignment nmd and TRIP13

DIOPT Version :9

• Sequence 1: NP_001285801.1
• Gene: nmd / 44021
• FlyBaseID: FBgn0005322
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_004228.1
• Gene: TRIP13 / 9319
• HGNCID: 12307
• Length: 432
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 80/330 - (24%)
• Similarity: 137/330 - (41%)
• Gaps: 92/330 - (27%)

  Fly    36 WMMNQMDPTSKNKKKAKVLAEEQLKRLAEQEGFKLRGQEFSDYELMIASHLVVPADITVSWADIA 100
            :.:|:..|:|:|       .||:.:                  .::.|:|.|:||      |:..
Human   100 FQLNEDGPSSEN-------LEEETE------------------NIIAANHWVLPA------AEFH 133

  Fly   101 GL-DSVIQE------LRESVVLPIQHKDLFKHSKLWQAPKGVLLHGPPGCGKTLIAKATAKEAGM 158
            || ||::.:      |.:.|:..:...|...:|.|....:.||||||||.|||.:.||.|::..:
Human   134 GLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTI 198

  Fly   159 R---------FINLDVAILTDKWYGESQKLTSAVFSLASRIEPCI--------IFIDEIDSFLRS 206
            |         .|.::...|..||:.||.||.:.:|   .:|:..|        :.|||::|...:
Human   199 RLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMF---QKIQDLIDDKDALVFVLIDEVESLTAA 260

  Fly   207 RN-----MNDHEATAMMKTQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVRRMPAQFHIGLP 266
            ||     ....:|..::......: |.:..::|  |:::..:|..:.:|.|.|.|...:.:||.|
Human   261 RNACRAGTEPSDAIRVVNAVLTQI-DQIKRHSN--VVILTTSNITEKIDVAFVDRADIKQYIGPP 322

  Fly   267 SETQRKDILKLILQSEEVSQDVDLNRLSKLTNGFSGSDLREMCRNASVYRMRQLITSRDPSATAL 331
            |...   |.|:.|                       |.|.|:.:...:|..:||:|.|:......
Human   323 SAAA---IFKIYL-----------------------SCLEELMKCQIIYPRQQLLTLRELEMIGF 361

  Fly   332 DRNNV 336
            ..|||
Human   362 IENNV 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	43/155 (28%)
		AAA	135..265	CDD:278434	42/151 (28%)
TRIP13	NP_004228.1	SpoVK	<136..360	CDD:223540	63/255 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810