Protein Alignment nmd and PEX6

DIOPT Version :10

• Sequence 1: NP_609373.1
• Gene: nmd / 44021
• FlyBaseID: FBgn0005322
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_014070.1
• Gene: PEX6 / 855387
• SGDID: S000005273
• Length: 1030
• Species: Saccharomyces cerevisiae
• Alignment Length: 403
• Identity: 116/403 - (28%)
• Similarity: 197/403 - (48%)
• Gaps: 68/403 - (16%)

  Fly     1 MDNFGLGG-SDLSKGQIFQVLVRLSVASLITYYSVKWMMNQMDPTSK---NKKKAKVLAEEQLKR 61
            |||..... |..|.|     |..|.:.|::.       ..:|..|::   ..||...|.:..|
Yeast   650 MDNISFSSLSSYSAG-----LTPLDIKSIVE-------TARMTATARFYQESKKCGWLPQSIL-- 700

  Fly    62 LAEQEGFKLRGQEFSDYELMIASHLVVPADITVSWADIAGLDSVIQELRESVVLPIQHKDLFKHS 126
            :.:::..|...:..:::.:.|.:    |....|:|.||.|:|.|..|:.:::.:|::|.:||...
Yeast   701 ITQEDLSKATSKARNEFSVSIGA----PQIPNVTWDDIGGIDFVKGEILDTIDMPLKHPELFTSG 761

  Fly   127 KLWQAPKGVLLHGPPGCGKTLIAKATAKEAGMRFINLDVAILTDKWYGESQKLTSAVFSLASRIE 191
              .:...|:|.:||||.||||:|||.|....:.|.::....|.:.:.|||:.....||..|...:
Yeast   762 --MKKRSGILFYGPPGTGKTLMAKAIATNFSLNFFSVKGPELLNMYIGESEANVRRVFQKAREAK 824

  Fly   192 PCIIFIDEIDSFLRSRNMNDHEATAMMK---TQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAI 253
            ||:||.|||||....|. |..::..:|.   :|.:...||:||:|:. |.|:||||||..||:|:
Yeast   825 PCVIFFDEIDSVAPKRG-NQGDSGGVMDRIVSQLLAELDGMSTDADG-VFVIGATNRPDLLDEAL 887

  Fly   254 VRRMPAQF----HIGLP-SETQRKDILKLILQSEEVSQDVDLNRLSKLTN-GFSGSDLREMCRNA 312
            :|  |.:|    ::|:| ::|::.:||:.:.:...:..||.|..|:||.. .::|:|...:|.:|
Yeast   888 LR--PGRFDKLLYLGIPDTDTKQLNILEALTRKFVLDNDVKLIELAKLCPFNYTGADFYALCSDA 950

  Fly   313 SVYRMRQL------------------ITSR---DPSATALDRNNVRITMDDLLGSHLKIKESKMH 356
            .:..|.::                  |::|   |..||..| ..|.:.|:|.|      |..:..
Yeast   951 MLNAMSRIARMVEKKVSQHNELTGENISTRRWFDKIATKED-TKVVVKMEDFL------KAQEQL 1008

  Fly   357 TSSLFLENRIELD 369
            |.|:   :|.||:
Yeast  1009 TPSV---SRAELN 1018

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_609373.1	RecA-like_ATAD1	98..263	CDD:410928	64/171 (37%)
		AAA_lid_3	287..323	CDD:465537	12/54 (22%)
PEX6	NP_014070.1	CDC48	<541..1021	CDD:273521	116/403 (29%)
		RecA-like_PEX6_r2	740..899	CDD:410935	60/164 (37%)