Protein Alignment nmd and MSP1

DIOPT Version :9

• Sequence 1: NP_001285801.1
• Gene: nmd / 44021
• FlyBaseID: FBgn0005322
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_011542.3
• Gene: MSP1 / 852915
• SGDID: S000003260
• Length: 362
• Species: Saccharomyces cerevisiae
• Alignment Length: 367
• Identity: 151/367 - (41%)
• Similarity: 224/367 - (61%)
• Gaps: 38/367 - (10%)

  Fly     9 SDLSKGQIFQVLVRLSVASLITYYSVKWMMNQMD--PTSKNKKKAKVLAEEQLKRLAEQEGFKLR 71
            :|||      |||...::   .||.|..::|.::  |.|...:::|.....|.::|.::.. .|.
Yeast    11 TDLS------VLVGTGIS---LYYLVSRLLNDVESGPLSGKSRESKAKQSLQWEKLVKRSP-ALA 65

  Fly    72 GQEFSDYELMIASHLVVPADITVSWADIAGLDSVIQELRESVVLPIQHKDLFKHSKLWQAPKGVL 136
            ......||..|.|.:|.|.:|.:::.||.|||.:|.:|.|||:.|:...:::.:|.|.|||.|||
Yeast    66 EVTLDAYERTILSSIVTPDEINITFQDIGGLDPLISDLHESVIYPLMMPEVYSNSPLLQAPSGVL 130

  Fly   137 LHGPPGCGKTLIAKATAKEAGMRFINLDVAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEID 201
            |:||||||||::|||.|||:|..||::.::.:.|||||||.|:..|:||||::::||||||||||
Yeast   131 LYGPPGCGKTMLAKALAKESGANFISIRMSSIMDKWYGESNKIVDAMFSLANKLQPCIIFIDEID 195

  Fly   202 SFLRSRNMNDHEATAMMKTQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVRRMPAQFHIGLP 266
            ||||.|:..|||.||.:|.:||.|||||..|..  |:::|||||..|:|.|.:||:|.:|.:.||
Yeast   196 SFLRERSSTDHEVTATLKAEFMTLWDGLLNNGR--VMIIGATNRINDIDDAFLRRLPKRFLVSLP 258

  Fly   267 SETQRKDILKLILQSEEVSQD-VDLNRLSKLTNGFSGSDLREMCRNAS-------VYRMRQLITS 323
            ...||..||.::|:..::.:| .||..::..|.|||||||:|:||.|:       :.:.||||.|
Yeast   259 GSDQRYKILSVLLKDTKLDEDEFDLQLIADNTKGFSGSDLKELCREAALDAAKEYIKQKRQLIDS 323

  Fly   324 RDPSATALDRNNVRITMDDLLGSHLKIK--ESKMHTSSLFLE 363
                 ..:|.|:.         |.|||:  ::|..|..|.::
Yeast   324 -----GTIDVNDT---------SSLKIRPLKTKDFTKKLRMD 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	77/133 (58%)
		AAA	135..265	CDD:278434	75/129 (58%)
MSP1	NP_011542.3	MDN1	<10..>164	CDD:227596	60/162 (37%)
		RecA-like_ATAD1	92..255	CDD:410928	92/164 (56%)
		AAA_lid_3	280..319	CDD:407720	14/38 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346440
Domainoid	1	1.000	166	1.000	Domainoid score	I808
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5960
Inparanoid	1	1.050	262	1.000	Inparanoid score	I622
Isobase	1	0.950	-	0	Normalized mean entropy	S651
OMA	1	1.010	-	-		QHG53576
OrthoFinder	1	1.000	-	-		FOG0002611
OrthoInspector	1	1.000	-	-		otm46518
orthoMCL	1	0.900	-	-		OOG6_103164
Panther	1	1.100	-	-	LDO	PTHR45644
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1910
SonicParanoid	1	1.000	-	-		X1716
TreeFam	1	0.960	-	-
	16	15.740