Protein Alignment nmd and vps4a

DIOPT Version :10

• Sequence 1: NP_609373.1
• Gene: nmd / 44021
• FlyBaseID: FBgn0005322
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_001070077.1
• Gene: vps4a / 767670
• ZFINID: ZDB-GENE-060929-388
• Length: 440
• Species: Danio rerio
• Alignment Length: 311
• Identity: 115/311 - (36%)
• Similarity: 180/311 - (57%)
• Gaps: 24/311 - (7%)

  Fly    45 SKNKKKAKVLAEEQL--KRLAEQEGFKLRGQEFSDYELMIASHLVVPADITVSWADIAGLDSVIQ 107
            :|:|:..|.:.|.|.  |..::.||.....::..:: ||.|   :|.....|.|:|:|||:...:
Zfish    76 NKDKQGKKPVKETQSNDKSDSDSEGENPEKKKLQEH-LMGA---IVMEKPNVRWSDVAGLEGAKE 136

  Fly   108 ELRESVVLPIQHKDLFKHSKL-WQAPKGVLLHGPPGCGKTLIAKATAKEA-GMRFINLDVAILTD 170
            .|:|:|:|||:...||...:. |   :|:||.||||.||:.:|||.|.|| ...|.::..:.|..
Zfish   137 ALKEAVILPIKFPHLFTGKRTPW---RGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMS 198

  Fly   171 KWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLRSRNMNDHEATAMMKTQFMMLWDGLSTNANS 235
            ||.|||:||...:|.||.:.:|.||||||:||...|||.|:.||...:||:|::...|:..| |.
Zfish   199 KWLGESEKLVKNLFDLARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNN-ND 262

  Fly   236 TVIVMGATNRPQDLDKAIVRRMPAQFHIGLPSETQRKDILKLILQSEEVS-QDVDLNRLSKLTNG 299
            .::|:||||.|..||.||.||...:.:|.||.|..|..:.:|.|.:...| .:.||.:|::.|:|
Zfish   263 GILVLGATNIPWVLDAAIRRRFEKRIYIPLPEEPARSAMFRLHLGNTPHSLTEADLRQLARKTDG 327

  Fly   300 FSGSDLREMCRNASVYRMRQLITS------RDPSATALDRNNVRITMDDLL 344
            :||:|:..:.|:|.:..:|::.::      |.||     |:|..:.:||||
Zfish   328 YSGADISIIVRDALMQPVRKVQSATHFKKVRGPS-----RSNSAVIVDDLL 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_609373.1	RecA-like_ATAD1	98..263	CDD:410928	73/166 (44%)
		AAA_lid_3	287..323	CDD:465537	11/35 (31%)
vps4a	NP_001070077.1	MIT_VPS4	4..79	CDD:239141	1/2 (50%)
		RecA-like_VPS4	120..290	CDD:410929	75/173 (43%)
		AAA_lid_3	317..358	CDD:465537	11/40 (28%)
		Vps4_C	373..>403	CDD:462762	1/1 (100%)