DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmd and Spata5l1

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001103117.1	Gene:	Spata5l1 / 691729	RGDID:	1595990	Length:	747	Species:	Rattus norvegicus

Alignment Length:	278	Identity:	88/278 - (31%)
Similarity:	140/278 - (50%)	Gaps:	28/278 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 PADITVSWADIAGLDSVIQELRESVVLPIQHKDLFKHSKLWQAPKGVLLHGPPGCGKTLIAKATA 153
            |.::|     :.||......|||.:.||:.:........| ..|:||||.||||.|||.:.:|.|
  Rat   190 PGEVT-----LGGLSETADSLRELLRLPLCYPLALAALGL-AVPRGVLLAGPPGVGKTQLVRAVA 248

  Fly   154 KEAGMRFINLDVAILTDKWYGESQKLTSAVF----SLASRIEPCIIFIDEIDSFLRSRNMNDHEA 214
            :|||...:.:....|.....||:::....||    .|||| .|.::|:||:|:....|.......
  Rat   249 REAGAELLAVSAPALQGTRPGETEENVRRVFQRAQELASR-GPSLLFLDEVDALCPRRGGPQRAP 312

  Fly   215 TAMMKTQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVRRMPAQFH----IGLPSETQRKDIL 275
            .:.:..|.:.|.||:  :.:..|:|:||||||.:||.|:  |.|.:|.    ||.|:..||:.||
  Rat   313 ESRVVAQVLTLLDGI--HGDREVVVVGATNRPDELDPAL--RRPGRFDREVIIGTPTLKQREAIL 373

  Fly   276 KLILQSEEVSQDVDLNRLSKLTNGFSGSDLREMCRNASVYRMRQLITSRDPSATALDRNNVRITM 340
            .:|.....:|..:||..|:::|.|:.|:||..:||.|:...:.:         ...::||.:|..
  Rat   374 GVITSKMPISSHIDLGLLAEMTVGYVGADLTALCREAATCALLK---------NEKNQNNPKIEE 429

  Fly   341 DDLLGSHLKIKESKMHTS 358
            .|.|.:..|::.|...:|
  Rat   430 TDFLEAFKKVQPSSFRSS 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	52/141 (37%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	49/137 (36%)
Spata5l1	NP_001103117.1	CDC48	14..738	CDD:273521	88/278 (32%)
		AAA	230..362	CDD:278434	48/136 (35%)
		AAA	496..646	CDD:278434
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900