DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmd and Atad1

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_080763.2	Gene:	Atad1 / 67979	MGIID:	1915229	Length:	361	Species:	Mus musculus

Alignment Length:	345	Identity:	192/345 - (55%)
Similarity:	265/345 - (76%)	Gaps:	9/345 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LSKGQIFQVLVRLSVASLITYYSVKWMMNQMDPTSKNKKKAKVLAEEQLKRLAEQEGFKLRGQEF 75
            ||:.::..::.||::...:||:::|||::.:|||    :|.||.|::|.::|.:|.|.|  ..:.
Mouse    11 LSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDPT----RKQKVEAQKQAEKLMKQIGVK--NVKL 69

  Fly    76 SDYELMIASHLVVPADITVSWADIAGLDSVIQELRESVVLPIQHKDLFKHSKLWQAPKGVLLHGP 140
            |:||:.||:|||.|.::.|:|:||||||.||.:|:::|:|||:.|.||::|:|.|.||||||:||
Mouse    70 SEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGP 134

  Fly   141 PGCGKTLIAKATAKEAGMRFINLDVAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLR 205
            |||||||||||||||||.|||||..:.||||||||||||.:||||||.:::|.||||||||||||
Mouse   135 PGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLR 199

  Fly   206 SRNMNDHEATAMMKTQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVRRMPAQFHIGLPSETQ 270
            :|:.:|||||||||.|||.|||||.|:.:..||||||||||||||.||:||||.:|||..|:..|
Mouse   200 NRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQ 264

  Fly   271 RKDILKLILQSEEVSQDVDLNRLSKLTNGFSGSDLREMCRNASVYRMRQLITSRDPSATALDRNN 335
            |:.||||||::|.|.:.|||..:::.|:|||||||:||||:|::..:|:.:.|  .|..:.|.:.
Mouse   265 REAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNS--TSEESHDEDE 327

  Fly   336 VR-ITMDDLLGSHLKIKESK 354
            :| :...||..:..|:|:||
Mouse   328 IRPVQQQDLHRAIEKMKKSK 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	103/133 (77%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	100/129 (78%)
Atad1	NP_080763.2	RecA-like_ATAD1	92..257	CDD:410928	120/164 (73%)
Atad1	NP_080763.2	AAA_lid_3	282..321	CDD:407720	19/40 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	206	1.000	Domainoid score	I2905
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5960
Inparanoid	1	1.050	374	1.000	Inparanoid score	I2075
Isobase	1	0.950	-	0	Normalized mean entropy	S651
OMA	1	1.010	-	-		QHG53576
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002611
OrthoInspector	1	1.000	-	-		otm42449
orthoMCL	1	0.900	-	-		OOG6_103164
Panther	1	1.100	-	-	LDO	PTHR45644
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1910
SonicParanoid	1	1.000	-	-		X1716
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.810