Protein Alignment nmd and Fignl2

DIOPT Version :10

• Sequence 1: NP_609373.1
• Gene: nmd / 44021
• FlyBaseID: FBgn0005322
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_001201840.1
• Gene: Fignl2 / 668225
• MGIID: 3646919
• Length: 644
• Species: Mus musculus
• Alignment Length: 312
• Identity: 87/312 - (27%)
• Similarity: 142/312 - (45%)
• Gaps: 34/312 - (10%)

  Fly    63 AEQEGFKLRGQEFSDYELMIASHLVVPADITVSWADIAGLDSVIQELRESVVLPIQHKDLFKHSK 127
            ||..|...:|.:....||:  |..:|.....|.|||:||..::...|.|.::.|:........|.
Mouse   355 AEPSGEPAKGVDPGALELV--SSKMVDCGPPVQWADVAGQGALKAALEEELLWPLLRPPACPGSA 417

  Fly   128 LWQAPKGVLLHGPPGCGKTLIAKATAKEAGMRFINLDVAILTDKWYGESQKLTSAVFSLASRIEP 192
            |  .|:.||..||.||||.|:.:..|...|...:.|..|.|......|..:|..|.|:.|....|
Mouse   418 L--PPRTVLFFGPRGCGKALLGRCLATRLGATLLRLRGAGLAASGAVEGARLLQAAFAAARCRPP 480

  Fly   193 CIIFIDEIDSFLRSRNMNDHEATAMMKTQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVRRM 257
            .::.|.|:|:.|.:|     :..|.::...:...||........|:|:|.|:||..||:|..||.
Mouse   481 AVLLISELDALLPAR-----DDGASLRAPLLTCLDGSCGARADGVLVVGTTSRPAALDEATRRRF 540

  Fly   258 PAQFHIGLPSETQRKDILKLILQSEEVS-QDVDLNRLSKLTNGFSGSDLREMCRNAS----VYRM 317
            ..:|::.||....|..||:..|..:..: .:.:|..|.:.|.||||.:|.::|:.|:    :..:
Mouse   541 ALRFYVALPDGAARGQILQRALAQQGCALNERELAALVQGTQGFSGGELGQLCQQAAAEAGISGL 605

  Fly   318 RQLITSRDPSATALDRNNVRITMDDLLGSHLKIKESKMHTSSLFLENRIELD 369
            ::.::.:|..| ||.:          :||....||         |::.:|.|
Mouse   606 QRPLSYKDVEA-ALAK----------VGSRAPSKE---------LDSLVEWD 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_609373.1	RecA-like_ATAD1	98..263	CDD:410928	49/164 (30%)
		AAA_lid_3	287..323	CDD:465537	10/39 (26%)
Fignl2	NP_001201840.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	285..323
		P-loop containing Nucleoside Triphosphate Hydrolases	388..546	CDD:476819	49/164 (30%)