DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmd and Fignl1

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	XP_011242039.1	Gene:	Fignl1 / 60530	MGIID:	1890648	Length:	692	Species:	Mus musculus

Alignment Length:	293	Identity:	103/293 - (35%)
Similarity:	168/293 - (57%)	Gaps:	26/293 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 NQMDPTSKNKKKAKV----------LAEEQLKRLAEQEGFKLRGQEFSDYELMIASHLVVPADIT 93
            |:.|.:.::.||.|.          |.::.||.: |....:|...|..|:            ...
Mouse   364 NKQDGSEQHAKKHKSSRAGSAEPAHLTDDCLKNV-EPRMVELIMNEIMDH------------GPP 415

  Fly    94 VSWADIAGLDSVIQELRESVVLPIQHKDLFKHSKLWQAPKGVLLHGPPGCGKTLIAKATAKEAGM 158
            |.|.||||::.....::|.||.|:...|:|  :.|...|||:||.||||.|||||.|..|.::|.
Mouse   416 VHWDDIAGVEFAKATIKEIVVWPMMRPDIF--TGLRGPPKGILLFGPPGTGKTLIGKCIASQSGA 478

  Fly   159 RFINLDVAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLRSRNMNDHEATAMMKTQFM 223
            .|.::..:.||.||.||.:|:..|:|::|...:|.:||||||||.|..|...:||::..:||:|:
Mouse   479 TFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFL 543

  Fly   224 MLWDGLSTNANSTVIVMGATNRPQDLDKAIVRRMPAQFHIGLPSETQRKDILKLILQSEEVS-QD 287
            :..||.:|::...::|:|||||||::|:|..||:..:.:|.||..:.||.|:..::..|:.. .|
Mouse   544 VQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVGNLMSKEQCCLSD 608

  Fly   288 VDLNRLSKLTNGFSGSDLREMCRNASVYRMRQL 320
            .:.:.:.:.::||||:|:.::||.||:..:|.|
Mouse   609 EETDLVVQQSDGFSGADMTQLCREASLGPIRSL 641

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	60/133 (45%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	57/129 (44%)
Fignl1	XP_011242039.1	RecA-like_Figl-1	398..583	CDD:410933	76/198 (38%)
		AAA_lid_3	608..>639	CDD:407720	10/30 (33%)
		Vps4_C	<649..689	CDD:401324
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810