DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmd and zgc:136908

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001035017.1	Gene:	zgc:136908 / 563679	ZFINID:	ZDB-GENE-060312-22	Length:	805	Species:	Danio rerio

Alignment Length:	318	Identity:	108/318 - (33%)
Similarity:	157/318 - (49%)	Gaps:	56/318 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 ITYYSVKWMMNQMDPTSKNKKKAKVLAEEQLKRLAEQEGFKLRGQEFSDYELMIASHLVVPADIT 93
            :|....||.::|.:|::..:...:|                              .|
Zfish   449 VTMDDFKWALSQSNPSALRETVVEV------------------------------PH-------- 475

  Fly    94 VSWADIAGLDSVIQELRESVVLPIQHKDLFKHSKLWQAP-KGVLLHGPPGCGKTLIAKATAKEAG 157
            |:|.||.|||.|.:||:|.|..|:::.|  |..|....| :|||.:|||||||||:|||.|.|..
Zfish   476 VNWEDIGGLDEVKRELQELVQYPVEYPD--KFLKFGMTPSRGVLFYGPPGCGKTLLAKAIANECQ 538

  Fly   158 MRFINLDVAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLRSRNMNDHE---ATAMMK 219
            ..|:::....|...|:|||:.....||..|.:..|||:|.||:||..::|.....:   |...:.
Zfish   539 ANFVSIKGPELLTMWFGESEANVRDVFDKARQAAPCILFFDELDSIAKARGGGAGDAGGAADRVI 603

  Fly   220 TQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVR--RMPAQFHIGLPSETQRKDILKLILQSE 282
            .|.:...||::...|  |.::||||||..:|.||:|  |:....:|.||....|..||:..|:..
Zfish   604 NQILTEMDGMTNKKN--VFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDMPSRTAILRANLRKS 666

  Fly   283 EVSQDVDLNRLSKLTNGFSGSDLREMCRNASVYRMRQLI-----TSRDPSA---TALD 332
            .|::||||..|||:|.||||:||.|:|:.|....:|:.|     ..|...|   ||:|
Zfish   667 PVAKDVDLMYLSKITEGFSGADLTEICQRACKLAIREAIEAEIRAERQRQARKETAMD 724

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	54/139 (39%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	52/134 (39%)
zgc:136908	NP_001035017.1	CDC48	27..766	CDD:273521	108/318 (34%)
		CDC48_N	27..109	CDD:280513
		CDC48_2	133..193	CDD:215011
		AAA	243..372	CDD:278434
		AAA	516..649	CDD:278434	52/134 (39%)
		Vps4_C	<731..762	CDD:286426
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900