DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmd and nsfb

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001019625.2	Gene:	nsfb / 554200	ZFINID:	ZDB-GENE-050808-1	Length:	747	Species:	Danio rerio

Alignment Length:	374	Identity:	99/374 - (26%)
Similarity:	161/374 - (43%)	Gaps:	86/374 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 MDP--------TSKNKK--------KAKVLAEEQLKRLAEQEGFKLRGQEFSDYELMIASHLVVP 89
            |||        :||..|        .::|:.|:     ||.....|.|:.    :...:...::.
Zfish   155 MDPSILRGEQNSSKKHKIDIGLLHGNSQVIFEK-----AESSSVNLIGKA----KTKGSRQSIIN 210

  Fly    90 ADITVSWADIAGLDSVIQEL-RESVVLPIQHKDLF-----KHSKLWQAPKGVLLHGPPGCGKTLI 148
            .|.......|.|||....:: |.:....:...|:.     ||      .||:||:|||||||||:
Zfish   211 PDWNFERMGIGGLDKEFSDIFRRAFASRVFPPDIVEQMGCKH------VKGILLYGPPGCGKTLM 269

  Fly   149 AKATAKEAGMR---FINLDVAILTDKWYGESQKLTSAVFS--------LASRIEPCIIFIDEIDS 202
            |:...|....|   .:| ...|| :|:.|||:.....:|:        |.:.....||..||||:
Zfish   270 ARQIGKMLNAREPKVVN-GPEIL-NKYVGESEANIRKLFADAEEEQKRLGANSGLHIIIFDEIDA 332

  Fly   203 FLRSR-----NMNDHEATAMMKTQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVR--RMPAQ 260
            ..:.|     :...|:...   .|.:...||:....|  ::|:|.||||..:|:|::|  |:..:
Zfish   333 ICKQRGSMAGSTGVHDTVV---NQLLSKIDGVEQLNN--ILVIGMTNRPDLIDEALLRPGRLEVK 392

  Fly   261 FHIGLPSETQRKDILKL----ILQSEEVSQDVDLNRLSKLTNGFSGSDLREMCRNASVYRMRQLI 321
            ..||||.||.|..||.:    :.||..:::|||:..|:..|..:||::|..:.|.|
Zfish   393 MEIGLPDETGRVQILNIHTAKMKQSNMLAKDVDVKELAVETKNYSGAELEGLVRAA--------- 448

  Fly   322 TSRDPSATALDRN---NVRITMDDLLGSHLKIKESKMHTSSLFLENRIE 367
                 .:||::|:   ..::.:|......|::..|....|   |.|.|:
Zfish   449 -----QSTAMNRHIKATTQVEVDTEKAQTLQVSRSDFLAS---LNNDIK 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	49/151 (32%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	46/147 (31%)
nsfb	NP_001019625.2	CDC48_N	5..85	CDD:308138
		CDC48_2	111..183	CDD:215011	6/27 (22%)
		SpoVK	<220..490	CDD:223540	86/300 (29%)
		AAA	538..670	CDD:214640
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900