DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmd and fign

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	XP_021334341.1	Gene:	fign / 553599	ZFINID:	ZDB-GENE-050522-339	Length:	747	Species:	Danio rerio

Alignment Length:	263	Identity:	79/263 - (30%)
Similarity:	141/263 - (53%)	Gaps:	21/263 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 AEEQLKRLAEQEGFKLRGQEFSDYEL--MIASHLVVPADITVSWADIAGLDSVIQELRESVVLPI 117
            ||||||.              ||..|  |:.:.::.... .|.|:|||||:.....:::.|:.||
Zfish   446 AEEQLKN--------------SDASLVEMVTTEILQQTP-PVDWSDIAGLEMAKATIKDEVLWPI 495

  Fly   118 QHKDLFKHSKLWQAPKGVLLHGPPGCGKTLIAKATAKEAGMRFINLDVAILTDKWYGESQKLTSA 182
            ...|:|  |.|...|:.:||.||.|.|:||:.:..|.:.|..|:.|..:.|..||.||.:|:..|
Zfish   496 LRPDMF--SGLATLPRSILLFGPQGTGRTLLGRCMASQLGAAFLLLSGSALVTKWLGEGEKIVQA 558

  Fly   183 VFSLASRIEPCIIFIDEIDSFLRSRNMNDHEATAMMKTQFMMLWDGLSTNANSTVIVMGATNRPQ 247
            .|.:|...:|.::||.::|..|.|: :::......:|::.::..||:.::....|:|:.:|::|:
Zfish   559 SFLIARCRQPSVVFISDVDLLLSSQ-LSEESPVNRIKSELLLQLDGVLSSPEEHVLVVCSTSKPE 622

  Fly   248 DLDKAIVRRMPAQFHIGLPSETQRKDIL-KLILQSEEVSQDVDLNRLSKLTNGFSGSDLREMCRN 311
            ::|:::.|....:..:.||..|.|..|: :|:.|......|.::..|.:.|:||||.|:..:|:.
Zfish   623 EIDESLRRYFVKRLLVPLPDATARHQIISQLLSQHNYCLSDKEVTLLVQRTDGFSGLDVVRLCQE 687

  Fly   312 ASV 314
            |.|
Zfish   688 ALV 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	37/133 (28%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	36/129 (28%)
fign	XP_021334341.1	EBV-NA3	<174..300	CDD:332796
		Herpes_UL32	<270..>444	CDD:283680
		SpoVK	<464..734	CDD:223540	69/231 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810