Protein Alignment nmd and NVL

DIOPT Version :9

• Sequence 1: NP_001285801.1
• Gene: nmd / 44021
• FlyBaseID: FBgn0005322
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: XP_016856867.1
• Gene: NVL / 4931
• HGNCID: 8070
• Length: 917
• Species: Homo sapiens
• Alignment Length: 352
• Identity: 109/352 - (30%)
• Similarity: 181/352 - (51%)
• Gaps: 52/352 - (14%)

  Fly    42 DPTSKNKKKAK----------VLAEEQLKRLAEQEGFKLRGQEFSDYELMIAS---------HLV 87
            :|||:.:.:.:          .|:|||::.|.         .|.:|:.:.::|         .:.
Human   580 EPTSETQDELQRLLGLLRDQDPLSEEQMQGLC---------IELNDFIVALSSVQPSAKREGFVT 635

  Fly    88 VPADITVSWADIAGLDSVIQELRESVVLPIQHKDLFKHSKLWQAPKGVLLHGPPGCGKTLIAKAT 152
            ||   .|:||||..|:.:.:||..:::.|:::.|.||...| ..|.||||.|||||||||:|||.
Human   636 VP---NVTWADIGALEDIREELTMAILAPVRNPDQFKALGL-VTPAGVLLAGPPGCGKTLLAKAV 696

  Fly   153 AKEAGMRFINLDVAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLRSRNMNDHEATAM 217
            |.|:|:.||::....|.:.:.|||::....||..|....||:||.||:|:....|:..:..|:..
Human   697 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRETGASVR 761

  Fly   218 MKTQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVR--RMPAQFHIGLPSETQRKDILKLILQ 280
            :..|.:...|||  .|...|.:|.|||||..:|.||:|  |:.....:|||....|..|||.|.:
Human   762 VVNQLLTEMDGL--EARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPADRLAILKTITK 824

  Fly   281 S---EEVSQDVDLNRLS--KLTNGFSGSDLREMCRNASVYRMRQLITSRDPSATALDRNNVRITM 340
            :   ..:..||:|..::  ...:.::|:||..:.|.||:..:||.: :|..|..  ::..:::
Human   825 NGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEM-ARQKSGN--EKGELKV-- 884

  Fly   341 DDLLGSHLKIKES-KMHTSSLFLENRI 366
                 ||...:|: |...||:..:::|
Human   885 -----SHKHFEEAFKKVRSSISKKDQI 906

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	56/135 (41%)
		AAA	135..265	CDD:278434	53/131 (40%)
NVL	XP_016856867.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900