DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmd and Pex1

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_652016.1	Gene:	Pex1 / 45460	FlyBaseID:	FBgn0013563	Length:	1006	Species:	Drosophila melanogaster

Alignment Length:	302	Identity:	79/302 - (26%)
Similarity:	135/302 - (44%)	Gaps:	48/302 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 DIAGLDSVIQELRESVVLPIQHKDLFKHSKLWQAPKGVLLHGPPGCGKTLIAKATAKEAGMRFIN 162
            ::.||:||:..|.|.::.|.::..:|..|.| :...||||:||||.|||.:....|....:|.|:
  Fly   721 ELPGLESVVGVLEEVLMWPSRYPTIFNASPL-RNQAGVLLYGPPGTGKTYLVSQLATSWNLRIIS 784

  Fly   163 LDVAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLRSRNMNDHEATAMMKTQFMMLWD 227
            :....|..|:.|:|::....:|:.|....||::|.||.||....|..:....|..:..|.:...|
  Fly   785 VKGPELLAKYIGQSEENVRNLFNRARSARPCVLFFDEFDSLAPKRGHDSTGVTDRVVNQLLTELD 849

  Fly   228 GLSTNANSTVIVMGATNRPQDLDKAIVR--RMPAQFHIGLPSETQRKDILKLILQSEEVSQDVDL 290
            |:......|||  .||:||:.||.|::|  |:.......||....|..|.:.:..:..:.:.||.
  Fly   850 GVEGLQGVTVI--AATSRPELLDPALLRSGRIDRLVECPLPDAPARVRIFEALSSTLSLDECVDF 912

  Fly   291 NRLSKLTNGFSGSDLREMCRNASVYRMRQLI------------------------TSRDPSATAL 331
            :..:..|..::|:|::.:..:|::..:::.:                        |:| ||.:|.
  Fly   913 DWFAGKTANYTGADIQSILTSANMAAVKEALAQFGHEKLAKKISLKQKHLIESFQTTR-PSLSAS 976

  Fly   332 D-----RNNVRITMDDLLGSHLKIKESKMHTSSLFLENRIEL 368
            |     |...|.|             :|..||..|:..|..|
  Fly   977 DVAKYHRTYARFT-------------NKEKTSREFVAKRATL 1005

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	44/135 (33%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	43/131 (33%)
Pex1	NP_652016.1	PEX-1N	93..168	CDD:286361
		SpoVK	479..974	CDD:223540	68/256 (27%)
		P-loop_NTPase	480..604	CDD:304359
		AAA	757..887	CDD:278434	43/131 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900