DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment nmd and Nsf2

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001287318.1	Gene:	Nsf2 / 41694	FlyBaseID:	FBgn0266464	Length:	752	Species:	Drosophila melanogaster

Alignment Length:	338	Identity:	97/338 - (28%)
Similarity:	154/338 - (45%)	Gaps:	59/338 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 PTSKNKKKAKVLAEEQLK-RLAEQEGFKLRGQEFSDYELMIASHLVVPADITVSWADIAGLD--- 103
            |.::|.:..::|....:: ..||.....|:|:.    :..|....::..|.......|.|||
  Fly   172 PKTRNVRFGRILGNTVVQFEKAENSVLNLQGRS----KGKIVRQSIINPDWDFGKMGIGGLDKEF 232

  Fly   104 -SVIQELRESVVLPIQHKDL--FKHSKLWQAPKGVLLHGPPGCGKTLIAK-----ATAKEAGMRF 160
             ::.:....|.|.|.:..:.  .||      .||:||:||||.||||:|:     ..|:|.  :.
  Fly   233 NAIFRRAFASRVFPPELVEQLGIKH------VKGILLYGPPGTGKTLMARQIGTMLNAREP--KI 289

  Fly   161 INLDVAILTDKWYGESQKLTSAVFSLA----SRIEP----CIIFIDEIDSFLRSR-----NMNDH 212
            :| ...|| ||:.|||:.....:|:.|    .|:.|    .||..||||:..::|     |...|
  Fly   290 VN-GPQIL-DKYVGESEANIRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKARGSVAGNSGVH 352

  Fly   213 EATAMMKTQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVR--RMPAQFHIGLPSETQRKDIL 275
            :...   .|.:...||:....|  ::|:|.|||...:|:|::|  |:..|..|.||:|..|..||
  Fly   353 DTVV---NQLLAKIDGVEQLNN--ILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQIL 412

  Fly   276 ----KLILQSEEVSQDVDLNRLSKLTNGFSGSDLREMCRNASVYRMRQLITSR-----DPSATAL 331
                |.:....:::.|||.|.::..|..|||::|..:.|.|....|.:||.:.     ||.|
  Fly   413 NIHTKRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQSTAMNRLIKADSKVHVDPEA--- 474

  Fly   332 DRNNVRITMDDLL 344
             ...:|:|..|.|
  Fly   475 -MEKLRVTRADFL 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	51/153 (33%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	49/149 (33%)
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011
		AAA	259..404	CDD:214640	52/153 (34%)
		AAA	261..402	CDD:278434	49/149 (33%)
		AAA	543..674	CDD:214640
		P-loop_NTPase	544..>613	CDD:304359
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810