DRSC/TRiP Functional Genomics Resources

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Protein Alignment nmd and IQCA1L

DIOPT Version :9

Sequence 1:NP_001285801.1 Gene:nmd / 44021 FlyBaseID:FBgn0005322 Length:369 Species:Drosophila melanogaster
Sequence 2:NP_001291348.1 Gene:IQCA1L / 392843 HGNCID:22831 Length:818 Species:Homo sapiens


Alignment Length:366 Identity:80/366 - (21%)
Similarity:148/366 - (40%) Gaps:85/366 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 KKKAKVLAEEQLKRLAEQEGFKLRGQEFSDYELMIASHLVVPADITVSWADIAG----LDSVIQ- 107
            |||.|.|..:             |..| |.||.::.|.|:..:: :|:..|..|    |.|.:. 
Human   475 KKKEKDLTSD-------------RSVE-SLYEELVISGLLRKSE-SVALKDYIGDFLYLGSTLSL 524

  Fly   108 ----------ELRESV----VLPIQHKDLFKHSKLWQAP--KGVLLHGPPGCGKTLIAKATAKEA 156
                      ::|::|    ||.:...|:  |.   .||  :.:||.||.|.||.::.||...|.
Human   525 VKKLPMPSLFDIRQNVALYAVLRLGSPDI--HI---MAPLIRSILLVGPSGMGKKMLVKAVCTET 584

  Fly   157 GMRFINLDVAILTDKWYGE--SQKLTSAVFSLASRIEPCIIFIDEID-SFLRSRNMNDHEATAM- 217
            |....:|....|..|:.|.  :|.:...||.:|..::|.:|:|...: :|.:.....|.|.... 
Human   585 GANLFDLSPENLLGKYPGRNGAQMMVHIVFKVARLLQPSVIWIGNAEKNFYKKTPKEDKEMDPKR 649

  Fly   218 ----MKTQFMMLWDGLSTNANSTVIVMGATNRPQDLD-KAIVRRMPAQFHIGLPSETQRKDILKL 277
                :.....:|..|      ..|:::|.|:|||..: :.:.|.......:..|....|..:.|.
Human   650 IKKDLTKALRLLTPG------DRVMLIGTTSRPQLAEMRGLCRVYERILFMPRPDYASRYVLWKR 708

  Fly   278 ILQSEEV--SQDVDLNRLSKLTNGFSGSDLREMCRNASVYR------MRQLITSR--------DP 326
            ::::..:  :|.:|::.|:|:::|::...:.:..::....|      .|.|:.|.        ||
Human   709 MIEARGIQPTQHLDISALAKVSDGYTPGHILQAIQSVLSERRFLQLSKRPLVASEFLGQLVKLDP 773

  Fly   327 -------------SATALDRNNVRITMDDLLGSHLKIKESK 354
                         ..|.|.:.:::..||.|.....|:.:.|
Human   774 VYREEEESLKDWYFKTPLGKKSMKHRMDQLEAEEAKLDKEK 814

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nmdNP_001285801.1 AAA 132..266 CDD:214640 35/144 (24%)
AAA 135..265 CDD:278434 34/138 (25%)
IQCA1LNP_001291348.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 344..377
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 458..482 4/6 (67%)
SpoVK <561..734 CDD:223540 42/178 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 795..818 5/20 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0464
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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