DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmd and Pex6

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001027403.2	Gene:	Pex6 / 3772165	FlyBaseID:	FBgn0033564	Length:	899	Species:	Drosophila melanogaster

Alignment Length:	293	Identity:	91/293 - (31%)
Similarity:	151/293 - (51%)	Gaps:	17/293 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 QEFSDYELMIASHLVVPADITVSWADIAGLDSVIQELRESVVLPIQHKDLF-KHSKLWQAPKGVL 136
            :..:|.:...|..|..|....|.|:||.||..:..|::.|:.||::|..|. |:.:    ..|:|
  Fly   594 KNLTDMQSSFADSLGAPKVPKVYWSDIGGLAKLKDEIQSSIGLPLKHVHLMGKNLR----RSGIL 654

  Fly   137 LHGPPGCGKTLIAKATAKEAGMRFINLDVAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEID 201
            |:||||.||||:|||.|.|..:.|:::....|.:.:.|:|::....|||.|....||::|:||:|
  Fly   655 LYGPPGTGKTLVAKAVATECNLSFLSVQGPELLNMYVGQSEQNVREVFSRARSAAPCVLFLDELD 719

  Fly   202 SFLRSRNMNDHEATAM--MKTQFMMLWDGLST-NANSTVIVMGATNRPQDLDKAIVR--RMPAQF 261
            |...:|.:.......|  :.:|.:...||:|. :.:..:.::.|||||..:|.|::|  |....|
  Fly   720 SLAPNRGVAGDSGGVMDRVVSQLLAEMDGMSDGDTSKPIFILAATNRPDLIDPALLRPGRFDKLF 784

  Fly   262 HIGLPSETQRKDILKLILQSEEVSQD--VDLNRLS-KLTNGFSGSDLREMCRNASVYRMRQLI-- 321
            ::| |..|.......|..|::..:.|  ||:.::: :|.:..||:||..:|.||.:..:|:.|
  Fly   785 YVG-PCSTAEDKAAVLRAQTQRFALDAGVDMEQIAERLKSEMSGADLYSICSNAWLSAVRRTIDG 848

  Fly   322 -TSRDPSATALDRNNVRITMDDLLGSHLKIKES 353
             .|...|...|...||.:..:|...|..|...|
  Fly   849 HLSGTISEKELVPENVIVQEEDFTKSFNKFVPS 881

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	48/138 (35%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	46/134 (34%)
Pex6	NP_001027403.2	SpoVK	367..847	CDD:223540	81/257 (32%)
		P-loop_NTPase	367..492	CDD:304359
		AAA	653..787	CDD:278434	46/133 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910