DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nmd and atad1b

DIOPT Version :9

Sequence 1:	NP_001285801.1	Gene:	nmd / 44021	FlyBaseID:	FBgn0005322	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001019592.1	Gene:	atad1b / 368412	ZFINID:	ZDB-GENE-030616-44	Length:	362	Species:	Danio rerio

Alignment Length:	345	Identity:	193/345 - (55%)
Similarity:	260/345 - (75%)	Gaps:	12/345 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LSKGQIFQVLVRLSVASLITYYSVKWMMNQMDPTSKNKKKAKVLAEEQLKRLAEQEGFKLRGQEF 75
            |.:.::..:|.||::...:||:::|||::.:|||    :|.||.|::|.::|..|.|  ::..:.
Zfish    15 LGRNEVIGLLFRLTIFGAVTYFTIKWMVDAIDPT----RKQKVEAQKQAEKLMRQIG--VQNVKL 73

  Fly    76 SDYELMIASHLVVPADITVSWADIAGLDSVIQELRESVVLPIQHKDLFKHSKLWQAPKGVLLHGP 140
            |:||:.||:|||.|..:.::|.||||||.||.||:::|:||||.:.||:.|:|.|.||||||:||
Zfish    74 SEYEMSIAAHLVDPLTMQITWYDIAGLDEVITELKDTVILPIQKRHLFEGSRLLQPPKGVLLYGP 138

  Fly   141 PGCGKTLIAKATAKEAGMRFINLDVAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLR 205
            |||||||||||||||||.|||||..:.||||||||||||.:||||||.:::|.||||||||||||
Zfish   139 PGCGKTLIAKATAKEAGFRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLR 203

  Fly   206 SRNMNDHEATAMMKTQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVRRMPAQFHIGLPSETQ 270
            :|:.:|||||||||.|||.|||||.|:.|..||:|||||||||||.||:||||.:|||..|:..|
Zfish   204 NRSSSDHEATAMMKAQFMSLWDGLDTDYNCQVIIMGATNRPQDLDSAILRRMPTRFHINQPNARQ 268

  Fly   271 RKDILKLILQSEEVSQDVDLNRLSKLTNGFSGSDLREMCRNASVYRMRQLITSRDPSATALDRNN 335
            |||||||||::|.|...|:|:.::|.|:||||||||||||:|::..:|..:....|     :.:.
Zfish   269 RKDILKLILENENVESAVELSEIAKQTDGFSGSDLREMCRDAALLCVRDFVHQESP-----EEDF 328

  Fly   336 VR-ITMDDLLGSHLKIKESK 354
            :| |..:||..:..|:|:||
Zfish   329 IRPIRQEDLQRAIEKMKKSK 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nmd	NP_001285801.1	AAA	132..266	CDD:214640	103/133 (77%)
nmd	NP_001285801.1	AAA	135..265	CDD:278434	100/129 (78%)
atad1b	NP_001019592.1	AAA	129..258	CDD:214640	100/128 (78%)
atad1b	NP_001019592.1	AAA	133..261	CDD:278434	98/127 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	210	1.000	Domainoid score	I2755
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5960
Inparanoid	1	1.050	379	1.000	Inparanoid score	I2029
OMA	1	1.010	-	-		QHG53576
OrthoDB	1	1.010	-	-		D1430018at2759
OrthoFinder	1	1.000	-	-		FOG0002611
OrthoInspector	1	1.000	-	-		mtm6343
orthoMCL	1	0.900	-	-		OOG6_103164
Panther	1	1.100	-	-	LDO	PTHR45644
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1910
SonicParanoid	1	1.000	-	-		X1716
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870